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Andreas_Rebmann

They have a lovely list on their website

Financially: Securing funding during unstable economic climate. Maintaining and improving their programs that rely on international funding. Having reserves to respond to new emergencies.

Human Resources: Finding experienced and committed staff, and qualified medical staff.

Operations: Security in areas of conflict. Balancing speaking out with accessing populations. Accessing appropriate medical treatments.

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Zackery.White

Doctors without Borders (MSF) is an organization that provides emergnecy medical aid to communities affeted by conflict, epidemics, disasters, and more. It's composed of mostly physicians and other health care workers, but is accepting of individuals which will help it achieve it's goals. MSF takes a neutral stance on issues as they only strictly abide by medical ethics.

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jaostrander

They do not claim to  have a "new" way of providing care, but unlike other medical organizations they do not rely on support from governments or institutions so they are able to provide care independently and to those who need it despite the political or socioeconomic factors.