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pece_annotation_1472844513

tamar.rogoszinski
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This study is published in the Japanese Journal of Clinical Oncology. This journal is for clinical oncologists and publishes articles about medical oncology, clinical trials, radiology, surgery, basic research, epidemiology, and palliative care. It was established in 1971 as the first journal from Japan to publish clinical research on cancer in English. It is a sister-journal to the Journal of the National Cancer Institute. It is also linked through the Oxford Journals. 

pece_annotation_1472844704

tamar.rogoszinski
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The object of this study is to observe whether or not there was an overdiagnosis of thyroid cancer after the Fukushima nuclear disaster in 2011. They did this by comparing the observed prevalance of thyroid cancer in the Thyroid Screening Programme with the estimated historical controls on the assumption that there was neither nuclear accident nor screening intervention. 

pece_annotation_1472844848

tamar.rogoszinski
Annotation of
In response to

The article is published in the Japanese Journal of Clinical Oncology. It is meant for clinical oncologists and publishes articles on medical oncology, clinical trials, radiology, surgery, basic research, epidemiology, and palliative care. It was established in 1971 and is the first journal from Japan to publish clinical research on cancer in English. Since 1977, JJCO is a sister-journal to the Journal of the National Cancer Institute and is linked through Oxford Journals. 

pece_annotation_1472845180

tamar.rogoszinski
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They calculated the observed/expected (O/E) ratio of thyroid cancer prevalence for residents in Fukushima Prefecture that were below the age of 20. Observed prevalence was calculated by the number of thyroid cancer cases detected by the end of April 2015. The number of detected cases was corrected for screening rate by multiplying the inverse of the age-specific screening rate. The expected prevalence was obtained from another report, which was calulated using a life-table method using national estimates from 2001-10. Age-specific prevalence of thyroid cancer was estimated using the cumulative risk from 2010. The annual percent change of increasing cases of thyroid cancer was taken into account as well. 

pece_annotation_1472845426

tamar.rogoszinski
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This study would be useful because it shows the prevalence of overdiagnosis. It shows that while the nuclear disaster did cause an increase in the observed thyroid cancers, this was well above the expected number of cases. While they did not present the dangerous implications of overdiagnosis, this is something that could be researched further. It can be considered a good thing that these cases were found through the Program put in place, but can also cause harm if unnecessary radiation was administered.