Skip to main content

Search

"Antibiotic Resistance in Louisiana"

fdabramo

I situate my research at the crossroads of history, philosophy, sociology and anthropology of science. In the past, I have focused on epigenetics, environmental research, empirical bioethics and environmental justice, within and outside the academia, as you can read here, or here. Now I am focusing on antibiotic resistance, and I use it as a lens to interpret the contradictions of the last century derived by industrial production, environmental degradation and biomedical cultures.

What interests me is the (at that time) new epistemic discourse that since the Forties has been produced to explain morphological changes of organisms produce when they experience new environmental conditions or perturbations. Through an important experiment at the base of the so-called concept of genetic assimilation, Conrad H. Waddington showed that a thermic shock can produce changes in wings’ veins of fruit flies, changes that can eventually be inherited across generations, without the environmental trigger that caused them.

This focus on production and (genetic) storage of biological differences elicited by the environment is nowadays coupled with the knowledge produced through microbiome research that explains the phenotypic patterns that recur across generations.

In a thought-provoking twist, with microbiome research, the focus shifts from production and inheritance of biological differences to production and inheritance of biological similarities. Microbiome research shows that some phenotypic patterns are allowed by ecological communities of microorganisms composing all animals. Bacteria allow the development and functioning of our bodies within an epistemic framework that is now key to understand biology. The network of vessels composing mammals’ stomach is formed through cellular differentiation and expression of genes coordinated by bacteria. The same is true for our immune system that is coordinated by gut bacteria. Food, which is an important aspect of our lives also impacts on this microecology and mediates between our biological functions and functioning of means of production whose parts dedicated to food production have immense importance for our biology and our internal and external ecologies. Antibiotic resistance is one of the crossroads where culture, biology, history and the Anthropocene meet. Indeed, Antibiotic resistance shows that means of production of our societies have an even more widespread, deep and allegedly unexpected impact on the biology of animals and plants. The microorganism can indeed adapt to resist the selective toxicity of antibiotics. Moreover, bacteria can transfer their genetic code horizontally, by touch, so that we can acquire antibiotic resistance by eating food that functions as a vector, by hosting lice on our heads and many other contacts. Bacteria that are resistant to antibiotics that have been used as growth factors in animal husbandry and to prevent diseases in livestock and aquaculture, spread in natural ecosystems and can be found in wild species. Rivers and estuarine waters are places hosting antibiotic resistance.

Searching on PubMed (the search engine for biomedical literature) titles of articles containing the terms ‘antimicrobial’ and ‘Louisiana’ I retrieved just one twelve-years-old article. No results with terms such as 'Mississippi' or 'New Orleans'. The authors collected and analysed Oysters from both waters of Louisiana Gulf and in restaurants and food retailers in Baton Rouge. In most of the samples gathered, scientists recognised the presence of bacteria (Vibrio parahaemolyticus and Vibrio vulnificus) resistant to specific antimicrobials. Food production is indeed the first factor in terms of the quantity of antibiotics used. This use and related antibiotic resistance impact all the living beings present in a specific area, and can easily travel around the globe through many channels. As Littman & Viens have highlighted, a sustainable future is a future without antibiotics as “there may be no truly sustainable way of using antibiotics in the long-run, as microorganisms have shown to be almost infinitely adaptable since the first introduction of antibiotics” (Littman & Viens 2015). But in the meanwhile, we need to use them and antibiotic resistance is a phenomenon that can be better studied through environmental research, by analysing wild species and emissions nearby livestock, for instance.

The study that I retrieved focuses on Oysters. But what about antibiotic resistance conveyed through food that is consumed by the most?

What about exposures of communities that are living in highly polluted areas?

And what is the additive value on antibiotic resistance for individuals who experience the presence of industrial pollutants and that live in areas where cancer epidemics are registered?

In this respect, there is a strategy to cope with the issue of antibiotic resistance promoted by the Center for Disease Control and Prevention. The document doesn’t mention any action to monitor and regulate the production and usage of antibiotics in livestock. Nevertheless, the CDC wants to scrutinise, through genome sequencing, “Listeria, Salmonella, Campylobacter, and E. coli and uploads sequence data into PulseNet for nationwide monitoring of outbreaks and trends.” Moreover, the document reports that “In Fiscal Year 2019, Louisiana will begin simultaneously monitoring these isolates for resistance genes. When outbreaks are detected, local CDC-supported epidemiologists investigate the cases to stop spread.”

The questions that I would like to ask (to local ppl, activists, researchers, practitioners..) are:

What could be the epidemiologic characteristics (socioeconomic status, gender, residence..) of the populations more vulnerable to antibiotic resistance?

What is the additive role of antibiotic resistance for people living in highly polluted areas?

What is the impact of antibiotic resistance for people and patients living in areas where cancer incidence is high?

 

And on the long run I am interested in imagining possible strategies to not only living with the problem but also to tackle the problem itself, which means to develop strategies to answer the questions:

Why antibiotic resistance, which is known since a century, it’s a problem on the rise?

What is the role and interest of capitalism, in terms of profit-making of corporations, knowledge production and environmental degradation, in not being able to resolve antibiotic resistance?

What can be strategies of local communities to tackle the problem and to promote environmental justice in terms of alliances with ecologists, doctors, epidemiologists and other activists?

pece_annotation_1472748570

seanw146

1) Fukushima proved current standard ineffective. Fukushima was the worst nuclear accident since the Chernobyl incident over 25 years ago. Hundreds of thousands of people had to be relocated due to the radiation leaks—many to this day. The effects of the hundreds of thousands of gallons of radiation contaminated water released into the ocean are still not fully known.

                2) International groups called for agency to enforce as no current candidate is feasible. IAEA is large enough but not fully trusted to be the host as it promotes nuclear use and appeared to praise TEPCO and the handling of the Fukushima incident. The World Association of Nuclear Operators (WANO) is a better candidate but still faces the problem of appearing as a secretive organization keeping its member companies confidential. WANO also currently lacks the size and resources to build an international nuclear disaster strike team.

                3) The author stresses that good communication and cooperation are required for success of such an organization. For a response team to work at the international level, sharing of different countries’ reactor designs and other various trade secrets would be crucial. The expertise from operators, responders, and other professionals who have had hands-on experience from Fukushima and other nuclear disasters. It would take a sizable amount of funding for such an organization and maintain the capabilities as the author described. 

pece_annotation_1473029925

seanw146

The IAEA is based in Vienna, Austria. It is comprised of six main departments: Department of Nuclear Energy, Department of Nuclear Sciences and Applications, Department of Technical Cooperation, Department of Safeguards, Department of Management, and Department of Safety and Security. The IAEA employs over 2200 staff throughout the world. It has offices in Toronto and Tokyo and also holds research facilities in Monaco, Austria, and Seibersdorf. The main resource the IAEA provides to its member is nuclear knowledge and expertise in its various departments though countless publications.

pece_annotation_1480299651

seanw146

Miriam Ticktin is an associate Anthropology professor at The New School. She graduated with a PhD from Stanford University in 2002. “Miriam works at the intersections of the anthropology of medicine and science, law, and transnational and postcolonial feminist theory. Her research has focused in the broadest sense on what it means to make political claims in the name of a universal humanity: she has been interested in what these claims tell us about universalisms and difference, about who can be a political subject, on what basis people are included and excluded from communities, and how inequalities get instituted or perpetuated in this process. She is the author of Casualties of Care: Immigration and the Politics of Immigration and Humanitarianism in France (UC Press, 2011), co-editor of In the Name of Humanity: the Government of Threat and Care (with Ilana Feldman, Duke UP 2010), and a founding co-editor of the journal Humanity: An International Journal of Human Rights, Humanitarianism and Development.” (from her profile from The New School).

pece_annotation_1473633925

seanw146

There are several ways that this study can benefit technical professionals. By knowing the factors for the highest risk for communicable diseases, resources can be directed to mitigate the effects of a disaster. The more aware technical professionals are of the risks of communicable diseases, the more likely they will be able to identify when these situations are likely and prevent them from happening.

pece_annotation_1480314828

seanw146

This act was a win for all individuals in EMS as no EMT, nurse, or doctor would have to send a patient in critical need away because there was no one to foot the bill. This was a horrible position that put medical workers in the position of moral culpability for policy formed by higher-ups who never had to deal with the reality of their decisions.

pece_annotation_1474239249

seanw146

Emergency responders were not the main focus of the film but were portrayed as having to deal with difficult situations that they had little real control over, mostly because the state was portrayed as trying to do the right thing but making things worse. The consequences of the government fell on the emergency workers. The doctors and responders had to risk personal safety and had to deal with people not trusting them and ignoring their requests.

pece_annotation_1524443970

stephanie.niev…

After the storms, many towns affected came up with ways to increase protection in infrastructure. Town officials working alongside exerpts have been working to upgrade their plans on making their communities more resilient to natural disasters. There have also many several funds and donations for the towns affected by Sandy; there have also been ways on how to help prevent flooding in such areas. In the article, it discusses how "the DEP has worked with local officials to design a proposed $230 million federally-funded system of flood walls along the Hudson River for Hoboken and parts of Weehawken and Jersey City."