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"Antibiotic Resistance in Louisiana"

fdabramo

I situate my research at the crossroads of history, philosophy, sociology and anthropology of science. In the past, I have focused on epigenetics, environmental research, empirical bioethics and environmental justice, within and outside the academia, as you can read here, or here. Now I am focusing on antibiotic resistance, and I use it as a lens to interpret the contradictions of the last century derived by industrial production, environmental degradation and biomedical cultures.

What interests me is the (at that time) new epistemic discourse that since the Forties has been produced to explain morphological changes of organisms produce when they experience new environmental conditions or perturbations. Through an important experiment at the base of the so-called concept of genetic assimilation, Conrad H. Waddington showed that a thermic shock can produce changes in wings’ veins of fruit flies, changes that can eventually be inherited across generations, without the environmental trigger that caused them.

This focus on production and (genetic) storage of biological differences elicited by the environment is nowadays coupled with the knowledge produced through microbiome research that explains the phenotypic patterns that recur across generations.

In a thought-provoking twist, with microbiome research, the focus shifts from production and inheritance of biological differences to production and inheritance of biological similarities. Microbiome research shows that some phenotypic patterns are allowed by ecological communities of microorganisms composing all animals. Bacteria allow the development and functioning of our bodies within an epistemic framework that is now key to understand biology. The network of vessels composing mammals’ stomach is formed through cellular differentiation and expression of genes coordinated by bacteria. The same is true for our immune system that is coordinated by gut bacteria. Food, which is an important aspect of our lives also impacts on this microecology and mediates between our biological functions and functioning of means of production whose parts dedicated to food production have immense importance for our biology and our internal and external ecologies. Antibiotic resistance is one of the crossroads where culture, biology, history and the Anthropocene meet. Indeed, Antibiotic resistance shows that means of production of our societies have an even more widespread, deep and allegedly unexpected impact on the biology of animals and plants. The microorganism can indeed adapt to resist the selective toxicity of antibiotics. Moreover, bacteria can transfer their genetic code horizontally, by touch, so that we can acquire antibiotic resistance by eating food that functions as a vector, by hosting lice on our heads and many other contacts. Bacteria that are resistant to antibiotics that have been used as growth factors in animal husbandry and to prevent diseases in livestock and aquaculture, spread in natural ecosystems and can be found in wild species. Rivers and estuarine waters are places hosting antibiotic resistance.

Searching on PubMed (the search engine for biomedical literature) titles of articles containing the terms ‘antimicrobial’ and ‘Louisiana’ I retrieved just one twelve-years-old article. No results with terms such as 'Mississippi' or 'New Orleans'. The authors collected and analysed Oysters from both waters of Louisiana Gulf and in restaurants and food retailers in Baton Rouge. In most of the samples gathered, scientists recognised the presence of bacteria (Vibrio parahaemolyticus and Vibrio vulnificus) resistant to specific antimicrobials. Food production is indeed the first factor in terms of the quantity of antibiotics used. This use and related antibiotic resistance impact all the living beings present in a specific area, and can easily travel around the globe through many channels. As Littman & Viens have highlighted, a sustainable future is a future without antibiotics as “there may be no truly sustainable way of using antibiotics in the long-run, as microorganisms have shown to be almost infinitely adaptable since the first introduction of antibiotics” (Littman & Viens 2015). But in the meanwhile, we need to use them and antibiotic resistance is a phenomenon that can be better studied through environmental research, by analysing wild species and emissions nearby livestock, for instance.

The study that I retrieved focuses on Oysters. But what about antibiotic resistance conveyed through food that is consumed by the most?

What about exposures of communities that are living in highly polluted areas?

And what is the additive value on antibiotic resistance for individuals who experience the presence of industrial pollutants and that live in areas where cancer epidemics are registered?

In this respect, there is a strategy to cope with the issue of antibiotic resistance promoted by the Center for Disease Control and Prevention. The document doesn’t mention any action to monitor and regulate the production and usage of antibiotics in livestock. Nevertheless, the CDC wants to scrutinise, through genome sequencing, “Listeria, Salmonella, Campylobacter, and E. coli and uploads sequence data into PulseNet for nationwide monitoring of outbreaks and trends.” Moreover, the document reports that “In Fiscal Year 2019, Louisiana will begin simultaneously monitoring these isolates for resistance genes. When outbreaks are detected, local CDC-supported epidemiologists investigate the cases to stop spread.”

The questions that I would like to ask (to local ppl, activists, researchers, practitioners..) are:

What could be the epidemiologic characteristics (socioeconomic status, gender, residence..) of the populations more vulnerable to antibiotic resistance?

What is the additive role of antibiotic resistance for people living in highly polluted areas?

What is the impact of antibiotic resistance for people and patients living in areas where cancer incidence is high?

 

And on the long run I am interested in imagining possible strategies to not only living with the problem but also to tackle the problem itself, which means to develop strategies to answer the questions:

Why antibiotic resistance, which is known since a century, it’s a problem on the rise?

What is the role and interest of capitalism, in terms of profit-making of corporations, knowledge production and environmental degradation, in not being able to resolve antibiotic resistance?

What can be strategies of local communities to tackle the problem and to promote environmental justice in terms of alliances with ecologists, doctors, epidemiologists and other activists?

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stephanie.niev…

Several public officials were named in this article: Robert McDonnell, governor of Virginia, Jack Markell, governor of Delaware, Patty McQuillan, a member of North Carolina's emergency management agency, Chris Christie, governor of New Jersey, Mike Bloomberg, mayor of New York City, Andrew Cuomo, governor of New York, Tom Corbett, governor of Pennsylvania, Michael Nutter, mayor of Philadelphia, Leon Panetta, Defense Secretary, and President Obama.

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stephanie.niev…

There were several professional design teams a part of reaching a solution to make Newark more resilient to hurricanes. Among these groups, there was a group of students that had helped in planning. One of the teacher's in charge of a design group from NJIT had been teaching a master’s class in infrastructure planning. There were 15 students in the class that had helped her in her design strategies. After being into seven different teams, the students went out and did research in towns that were deeply affected by Hurricane Sandy. There were a range of majors among the students, from architecture to design or planning. Each student used his or her own knowledge and separate disciplines to come up with ideas to aid areas that were affected by Sandy.

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stephanie.niev…

Both the Federal Emergency Management Agency (FEMA) and Red Cross helped during this natural disaster. Also, New Jersey had sent out several sotrm warning and procedures on what to do if stuck in a troubling situation during the sotrm. New Jersey also sent out shelter locations to go to if necessary. In Newark, the public safety sent out several tips and methods to prevent any internal damage, such as flooding, in housing and what to store during the super storm.

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stephanie.niev…

The main point of this article was to illustrate the severity of the super storm Irene. It shows the stressed and frantic thought process and procedures before the storm. In addition, it shows the aftereffects of the storm and how many different places and people were affected greatly thoughout the East coast. These points are supported by quotes, statistics and overall analysis of the super storm itself.

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stephanie.niev…

A year after Hurricane Sandy, ten different design groups, filled with designers, architects, planners and engineers, decided to gather at NJIT to discuss ways on how to make Newark less vulnerable to hurricanes and other natural disasters. One team was lead by a professor at NJIT, who had four different proposals that will protect a wide portion of the coasts of New Jersey. Each of the teams came up with several ideas on how to make Newark more resilient to natural disasters.

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stephanie.niev…

There were several forms of resilience int eh article. The Federal Emergency Management Agency (FEMA) were preparing several emergency personnel are preparing all along the coast. In addition to this, there were several shelters open, one specfically at the John F. Kennedy Recreation Center. Many of the shelters had also teamed up with Red Cross to help during the storm.

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stephanie.niev…

The author of the article took several quotes from government officials to depict the severity of the situation: mainly taking quotes from governors and even the president to illustrate how the hurricane affected the surrounding communities and mentalities of those living in such towns. In addition, the author added statistics of the support relief and the number of deceased due to the storm. The author also discussed the background of many of the public transportation work shifts, such as airlfight and train systems: they were down becuase of the storm.

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stephanie.niev…

The largest risk at hand would be how the nautral disaster, Hurricane Sandy, affected the beaches of New Jersey, causing some the beaches to lose a significant amount of sand; this becomes a risk because the beaches weren't available to use. The beaches of New Jersey make most of the profit in tourism: the shore gaining $35.5 billion for tourism locations. This became a risk becuase there was money lost during and after the storm, as groups tried to repair the shores. In addition, the cost to repair the shores were extremely costly. Another group that received risks and hazards were the communities near the shores: they had to change their entire lifestyle when the beaches were destroyed after the storm. Those communities had to learn how to live without the beaches' resources and had to get accustomed to not going down to the shores while the beaches were being restored.