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"Antibiotic Resistance in Louisiana"

fdabramo

I situate my research at the crossroads of history, philosophy, sociology and anthropology of science. In the past, I have focused on epigenetics, environmental research, empirical bioethics and environmental justice, within and outside the academia, as you can read here, or here. Now I am focusing on antibiotic resistance, and I use it as a lens to interpret the contradictions of the last century derived by industrial production, environmental degradation and biomedical cultures.

What interests me is the (at that time) new epistemic discourse that since the Forties has been produced to explain morphological changes of organisms produce when they experience new environmental conditions or perturbations. Through an important experiment at the base of the so-called concept of genetic assimilation, Conrad H. Waddington showed that a thermic shock can produce changes in wings’ veins of fruit flies, changes that can eventually be inherited across generations, without the environmental trigger that caused them.

This focus on production and (genetic) storage of biological differences elicited by the environment is nowadays coupled with the knowledge produced through microbiome research that explains the phenotypic patterns that recur across generations.

In a thought-provoking twist, with microbiome research, the focus shifts from production and inheritance of biological differences to production and inheritance of biological similarities. Microbiome research shows that some phenotypic patterns are allowed by ecological communities of microorganisms composing all animals. Bacteria allow the development and functioning of our bodies within an epistemic framework that is now key to understand biology. The network of vessels composing mammals’ stomach is formed through cellular differentiation and expression of genes coordinated by bacteria. The same is true for our immune system that is coordinated by gut bacteria. Food, which is an important aspect of our lives also impacts on this microecology and mediates between our biological functions and functioning of means of production whose parts dedicated to food production have immense importance for our biology and our internal and external ecologies. Antibiotic resistance is one of the crossroads where culture, biology, history and the Anthropocene meet. Indeed, Antibiotic resistance shows that means of production of our societies have an even more widespread, deep and allegedly unexpected impact on the biology of animals and plants. The microorganism can indeed adapt to resist the selective toxicity of antibiotics. Moreover, bacteria can transfer their genetic code horizontally, by touch, so that we can acquire antibiotic resistance by eating food that functions as a vector, by hosting lice on our heads and many other contacts. Bacteria that are resistant to antibiotics that have been used as growth factors in animal husbandry and to prevent diseases in livestock and aquaculture, spread in natural ecosystems and can be found in wild species. Rivers and estuarine waters are places hosting antibiotic resistance.

Searching on PubMed (the search engine for biomedical literature) titles of articles containing the terms ‘antimicrobial’ and ‘Louisiana’ I retrieved just one twelve-years-old article. No results with terms such as 'Mississippi' or 'New Orleans'. The authors collected and analysed Oysters from both waters of Louisiana Gulf and in restaurants and food retailers in Baton Rouge. In most of the samples gathered, scientists recognised the presence of bacteria (Vibrio parahaemolyticus and Vibrio vulnificus) resistant to specific antimicrobials. Food production is indeed the first factor in terms of the quantity of antibiotics used. This use and related antibiotic resistance impact all the living beings present in a specific area, and can easily travel around the globe through many channels. As Littman & Viens have highlighted, a sustainable future is a future without antibiotics as “there may be no truly sustainable way of using antibiotics in the long-run, as microorganisms have shown to be almost infinitely adaptable since the first introduction of antibiotics” (Littman & Viens 2015). But in the meanwhile, we need to use them and antibiotic resistance is a phenomenon that can be better studied through environmental research, by analysing wild species and emissions nearby livestock, for instance.

The study that I retrieved focuses on Oysters. But what about antibiotic resistance conveyed through food that is consumed by the most?

What about exposures of communities that are living in highly polluted areas?

And what is the additive value on antibiotic resistance for individuals who experience the presence of industrial pollutants and that live in areas where cancer epidemics are registered?

In this respect, there is a strategy to cope with the issue of antibiotic resistance promoted by the Center for Disease Control and Prevention. The document doesn’t mention any action to monitor and regulate the production and usage of antibiotics in livestock. Nevertheless, the CDC wants to scrutinise, through genome sequencing, “Listeria, Salmonella, Campylobacter, and E. coli and uploads sequence data into PulseNet for nationwide monitoring of outbreaks and trends.” Moreover, the document reports that “In Fiscal Year 2019, Louisiana will begin simultaneously monitoring these isolates for resistance genes. When outbreaks are detected, local CDC-supported epidemiologists investigate the cases to stop spread.”

The questions that I would like to ask (to local ppl, activists, researchers, practitioners..) are:

What could be the epidemiologic characteristics (socioeconomic status, gender, residence..) of the populations more vulnerable to antibiotic resistance?

What is the additive role of antibiotic resistance for people living in highly polluted areas?

What is the impact of antibiotic resistance for people and patients living in areas where cancer incidence is high?

 

And on the long run I am interested in imagining possible strategies to not only living with the problem but also to tackle the problem itself, which means to develop strategies to answer the questions:

Why antibiotic resistance, which is known since a century, it’s a problem on the rise?

What is the role and interest of capitalism, in terms of profit-making of corporations, knowledge production and environmental degradation, in not being able to resolve antibiotic resistance?

What can be strategies of local communities to tackle the problem and to promote environmental justice in terms of alliances with ecologists, doctors, epidemiologists and other activists?

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 I researched more into why the fire department’s Radios were having difficulties and issues, especially on the higher floors. First, the agency primarily used VHF (very high frequency) radios which are better for long distance when there is line-of-sight form point-to-point with minimal obstructions. UHF operates on a higher frequency and thus transmits with shorter wave-lengths which is better for object penetration. There are many challenges with radio communications in a city like NYC, starting with the sheer fact that to transmit directly from the ground to the top requires going through over a hundred stories of steel and concrete.

The repeaters worked to an extent. We know that they were operational and working, at least partly, as they recorded the relayed transmissions. The police used a separate but almost identical repeater as the fire department with mostly success. The NYFD experienced more issues. I found reports that claimed from fire fighters in the towers that while the transmissions were getting through, they were not understood due to the loud working environment and congested radio traffic.

The Incident Command System was largely ineffective. The only agency that was properly trained in ICS was the fire department which made inter-agency command and control through ICS moot. It was because of the events on 9/11/2001 that resulted in the development of the Nation Incident Management System, by the Department of Homeland Security, which encompasses ICS and more. Federal funding for emergencies now requires that NIMS be used as well as all first responders that respond to hazardous materials incidents be trained in the ICS.

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Didier Fassin—

“Didier Fassin is an anthropologist and a sociologist who has conducted fieldwork in Senegal, Ecuador, South Africa, and France. Trained as a physician in internal medicine and public health, he dedicated his early research to medical anthropology, illuminating important dimensions of the AIDS epidemic, mortality disparities, and global health. He later developed the field of critical moral anthropology, which explores the historical, social, and political signification of moral forms involved in everyday judgment and action as well as in the making of international relations with humanitarianism. He recently conducted an ethnography of the state, through a study of urban policing as well as the justice and prison systems in France. His current work is on punishment, asylum, inequality, and the politics of life, and he is developing a reflection on the public presence of the social sciences. He occasionally writes for the French newspapers Le Monde and Libération. His recent books include The Empire of Trauma: An Inquiry Into the Condition of Victimhood (2009), Humanitarian Reason: A Moral History of the Present (2011), Enforcing Order: An Ethnography of Urban Policing (2013), At the Heart of the State: The Moral World of Institutions (2015), and Prison Worlds: An Ethnography of the Carceral Condition (2016).” (https://www.ias.edu/scholars/fassin)

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“Based upon research that the DRLA leadership has conducted with reputational leaders in the field, including leaders from within other premier academic institutions, international organizations, prestigious NGOs, the United Nations, the donor community, think tanks and the Red Cross movement, it is widely agreed that a systematic and interdisciplinary approach to leadership is widely needed in the community and insufficiently addressed in most academic programs. As Tulane University itself has exhibited such resilience and strength of leadership in the aftermath of Hurricane Katrina, it represents and ideal setting to support such an approach to disaster resilience leadership education and allows students to experience the living laboratory of recovery and resilience that is the city of New Orleans.” -- Louisiana Voluntary Organizations Active in Disasters.

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1) I did more research into our role and mental health in the EMS system as EMTs. I found this article to be particularly insightful: Managing Psychiatric Emergencies (http://www.emsworld.com/article/10931747/managing-psychiatric-emergencies).

2) Bettering and improving EMS care by bypassing EDs and transporting patients to mental hospitals.

(http://epmonthly.com/article/pilot-project-trains-ems-to-bypass-the-ed-with-mental-health-patients/)

3) Learned about FEMAs policies and programs for mental health following a disaster in the U.S. (https://www.fema.gov/recovery-directorate/crisis-counseling-assistance-training-program)

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The author of this article is Sonja D. Schmid. Sonja has degrees in science, technology and society (STS) as well as experience in organizational theory, disaster social issues, and studied risk in relation to different societies and cultures throughout the world.

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Every year the IAEA releases various reports on its members and the state of nuclear safety, safeguards implementation reports, nuclear technology review, and technical cooperation reports. These documents report the progress of the IAEA on accomplishing its mission statement.