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How does visualizing allows us to set the parameters to make the future vision a reality?

I situate my research at the crossroads of history, philosophy, sociology and anthropology of science. In the past, I have focused on epigenetics, environmental research, empirical bioethics and environmental justice, within and outside the academia, as you can read here, or here. Now I am focusing on antibiotic resistance, and I use it as a lens to interpret the contradictions of the last century derived by industrial production, environmental degradation and biomedical cultures.

What interests me is the (at that time) new epistemic discourse that since the Forties has been produced to explain morphological changes of organisms produce when they experience new environmental conditions or perturbations. Through an important experiment at the base of the so-called concept of genetic assimilation, Conrad H. Waddington showed that a thermic shock can produce changes in wings’ veins of fruit flies, changes that can eventually be inherited across generations, without the environmental trigger that caused them.

This focus on production and (genetic) storage of biological differences elicited by the environment is nowadays coupled with the knowledge produced through microbiome research that explains the phenotypic patterns that recur across generations.

In a thought-provoking twist, with microbiome research, the focus shifts from production and inheritance of biological differences to production and inheritance of biological similarities. Microbiome research shows that some phenotypic patterns are allowed by ecological communities of microorganisms composing all animals. Bacteria allow the development and functioning of our bodies within an epistemic framework that is now key to understand biology. The network of vessels composing mammals’ stomach is formed through cellular differentiation and expression of genes coordinated by bacteria. The same is true for our immune system that is coordinated by gut bacteria. Food, which is an important aspect of our lives also impacts on this microecology and mediates between our biological functions and functioning of means of production whose parts dedicated to food production have immense importance for our biology and our internal and external ecologies. Antibiotic resistance is one of the crossroads where culture, biology, history and the Anthropocene meet. Indeed, Antibiotic resistance shows that means of production of our societies have an even more widespread, deep and allegedly unexpected impact on the biology of animals and plants. The microorganism can indeed adapt to resist the selective toxicity of antibiotics. Moreover, bacteria can transfer their genetic code horizontally, by touch, so that we can acquire antibiotic resistance by eating food that functions as a vector, by hosting lice on our heads and many other contacts. Bacteria that are resistant to antibiotics that have been used as growth factors in animal husbandry and to prevent diseases in livestock and aquaculture, spread in natural ecosystems and can be found in wild species. Rivers and estuarine waters are places hosting antibiotic resistance.

Searching on PubMed (the search engine for biomedical literature) titles of articles containing the terms ‘antimicrobial’ and ‘Louisiana’ I retrieved just one twelve-years-old article. No results with terms such as 'Mississippi' or 'New Orleans'. The authors collected and analysed Oysters from both waters of Louisiana Gulf and in restaurants and food retailers in Baton Rouge. In most of the samples gathered, scientists recognised the presence of bacteria (Vibrio parahaemolyticus and Vibrio vulnificus) resistant to specific antimicrobials. Food production is indeed the first factor in terms of the quantity of antibiotics used. This use and related antibiotic resistance impact all the living beings present in a specific area, and can easily travel around the globe through many channels. As Littman & Viens have highlighted, a sustainable future is a future without antibiotics as “there may be no truly sustainable way of using antibiotics in the long-run, as microorganisms have shown to be almost infinitely adaptable since the first introduction of antibiotics” (Littman & Viens 2015). But in the meanwhile, we need to use them and antibiotic resistance is a phenomenon that can be better studied through environmental research, by analysing wild species and emissions nearby livestock, for instance.

The study that I retrieved focuses on Oysters. But what about antibiotic resistance conveyed through food that is consumed by the most?

What about exposures of communities that are living in highly polluted areas?

And what is the additive value on antibiotic resistance for individuals who experience the presence of industrial pollutants and that live in areas where cancer epidemics are registered?

In this respect, there is a strategy to cope with the issue of antibiotic resistance promoted by the Center for Disease Control and Prevention. The document doesn’t mention any action to monitor and regulate the production and usage of antibiotics in livestock. Nevertheless, the CDC wants to scrutinise, through genome sequencing, “Listeria, Salmonella, Campylobacter, and E. coli and uploads sequence data into PulseNet for nationwide monitoring of outbreaks and trends.” Moreover, the document reports that “In Fiscal Year 2019, Louisiana will begin simultaneously monitoring these isolates for resistance genes. When outbreaks are detected, local CDC-supported epidemiologists investigate the cases to stop spread.”

The questions that I would like to ask (to local ppl, activists, researchers, practitioners..) are:

What could be the epidemiologic characteristics (socioeconomic status, gender, residence..) of the populations more vulnerable to antibiotic resistance?

What is the additive role of antibiotic resistance for people living in highly polluted areas?

What is the impact of antibiotic resistance for people and patients living in areas where cancer incidence is high?

And on the long run I am interested in imagining possible strategies to not only living with the problem but also to tackle the problem itself, which means to develop strategies to answer the questions:

Why antibiotic resistance, which is known since a century, it’s a problem on the rise?

What is the role and interest of capitalism, in terms of profit-making of corporations, knowledge production and environmental degradation, in not being able to resolve antibiotic resistance?

What can be strategies of local communities to tackle the problem and to promote environmental justice in terms of alliances with ecologists, doctors, epidemiologists and other activists?

The U.S. Environmental Protection Agency’s Lead and Copper Rule regulates the presence of lead in drinking water. Under the rule, if more than 10 percent of samples test above 15 parts per billion, the federal lead “action level” is exceeded. An “action level” exceedance triggers mandatory requirements that a water system must perform. For Newark, these requirements include water quality monitoring, corrosion control treatment, source water monitoring and treatment, public education, and lead service line replacement. Newark must treat its water to guard against corrosion (pipe erosion and damage) to minimize lead “leaching” (when lead is dissolved from pipes or fixtures and transfers into the water) or flaking of small lead particles from pipes or fixtures into tap water.

The object of this study is to demonstrate with objective data that pollution in Newark is causing real damage. Especially for children, because they suffer from respiratory diseases such as asthma; which is more harmful to a developing organism like a child. It is important that we become aware that pollution damage is real, and that a part of the population that is really affected is the youngest.

I think it is an important step, clearly for presenting complaints, the problem will not be solved; we should all do it if we see something of this kind. In addition to the complaints, there are many steps to follow, such as organizing protests, taking care of daily consumption or becoming aware that a sustainable life is better for everyone.

The product used to measure the level is a portable air sensor; This product is an innovative development because as it says in the article Molly Greenberg allows to obtain air quality data, this is clearly a breakthrough since years ago getting this information was not possible or the process was much more complicated.

This artifact has great relevance because it allows to control and measure the levels of contamination in the air of Newark. This is very helpful in order to fight pollution and have more data to help us maintain air sustainability. Air pollution is one of the most developed pollutions today, any technological investment that helps to have more information about this is good to combat this problem.

The participation of the EPA in the improvement of air pollution in Newark has a great relevance because it is an organization that has the ability to invest money in technologies that allow to have a greater knowledge of the levels of air pollution. This allows you to prevent problems and have more information to fight them better.

The policy is that developers request environmental permits to inform the city of any environmental problems. The aim is to achieve sustainability and a safe environmental life for citizens. 

I think that if it is possible to reconcile both developments, since both are necessary for social development we should look for policies that help to live with both. If a sustainable use of the industry is made, it can offer favorable living conditions and at the same time not harm the environment.