Skip to main content

Search

"Antibiotic Resistance in Louisiana"

fdabramo

I situate my research at the crossroads of history, philosophy, sociology and anthropology of science. In the past, I have focused on epigenetics, environmental research, empirical bioethics and environmental justice, within and outside the academia, as you can read here, or here. Now I am focusing on antibiotic resistance, and I use it as a lens to interpret the contradictions of the last century derived by industrial production, environmental degradation and biomedical cultures.

What interests me is the (at that time) new epistemic discourse that since the Forties has been produced to explain morphological changes of organisms produce when they experience new environmental conditions or perturbations. Through an important experiment at the base of the so-called concept of genetic assimilation, Conrad H. Waddington showed that a thermic shock can produce changes in wings’ veins of fruit flies, changes that can eventually be inherited across generations, without the environmental trigger that caused them.

This focus on production and (genetic) storage of biological differences elicited by the environment is nowadays coupled with the knowledge produced through microbiome research that explains the phenotypic patterns that recur across generations.

In a thought-provoking twist, with microbiome research, the focus shifts from production and inheritance of biological differences to production and inheritance of biological similarities. Microbiome research shows that some phenotypic patterns are allowed by ecological communities of microorganisms composing all animals. Bacteria allow the development and functioning of our bodies within an epistemic framework that is now key to understand biology. The network of vessels composing mammals’ stomach is formed through cellular differentiation and expression of genes coordinated by bacteria. The same is true for our immune system that is coordinated by gut bacteria. Food, which is an important aspect of our lives also impacts on this microecology and mediates between our biological functions and functioning of means of production whose parts dedicated to food production have immense importance for our biology and our internal and external ecologies. Antibiotic resistance is one of the crossroads where culture, biology, history and the Anthropocene meet. Indeed, Antibiotic resistance shows that means of production of our societies have an even more widespread, deep and allegedly unexpected impact on the biology of animals and plants. The microorganism can indeed adapt to resist the selective toxicity of antibiotics. Moreover, bacteria can transfer their genetic code horizontally, by touch, so that we can acquire antibiotic resistance by eating food that functions as a vector, by hosting lice on our heads and many other contacts. Bacteria that are resistant to antibiotics that have been used as growth factors in animal husbandry and to prevent diseases in livestock and aquaculture, spread in natural ecosystems and can be found in wild species. Rivers and estuarine waters are places hosting antibiotic resistance.

Searching on PubMed (the search engine for biomedical literature) titles of articles containing the terms ‘antimicrobial’ and ‘Louisiana’ I retrieved just one twelve-years-old article. No results with terms such as 'Mississippi' or 'New Orleans'. The authors collected and analysed Oysters from both waters of Louisiana Gulf and in restaurants and food retailers in Baton Rouge. In most of the samples gathered, scientists recognised the presence of bacteria (Vibrio parahaemolyticus and Vibrio vulnificus) resistant to specific antimicrobials. Food production is indeed the first factor in terms of the quantity of antibiotics used. This use and related antibiotic resistance impact all the living beings present in a specific area, and can easily travel around the globe through many channels. As Littman & Viens have highlighted, a sustainable future is a future without antibiotics as “there may be no truly sustainable way of using antibiotics in the long-run, as microorganisms have shown to be almost infinitely adaptable since the first introduction of antibiotics” (Littman & Viens 2015). But in the meanwhile, we need to use them and antibiotic resistance is a phenomenon that can be better studied through environmental research, by analysing wild species and emissions nearby livestock, for instance.

The study that I retrieved focuses on Oysters. But what about antibiotic resistance conveyed through food that is consumed by the most?

What about exposures of communities that are living in highly polluted areas?

And what is the additive value on antibiotic resistance for individuals who experience the presence of industrial pollutants and that live in areas where cancer epidemics are registered?

In this respect, there is a strategy to cope with the issue of antibiotic resistance promoted by the Center for Disease Control and Prevention. The document doesn’t mention any action to monitor and regulate the production and usage of antibiotics in livestock. Nevertheless, the CDC wants to scrutinise, through genome sequencing, “Listeria, Salmonella, Campylobacter, and E. coli and uploads sequence data into PulseNet for nationwide monitoring of outbreaks and trends.” Moreover, the document reports that “In Fiscal Year 2019, Louisiana will begin simultaneously monitoring these isolates for resistance genes. When outbreaks are detected, local CDC-supported epidemiologists investigate the cases to stop spread.”

The questions that I would like to ask (to local ppl, activists, researchers, practitioners..) are:

What could be the epidemiologic characteristics (socioeconomic status, gender, residence..) of the populations more vulnerable to antibiotic resistance?

What is the additive role of antibiotic resistance for people living in highly polluted areas?

What is the impact of antibiotic resistance for people and patients living in areas where cancer incidence is high?

 

And on the long run I am interested in imagining possible strategies to not only living with the problem but also to tackle the problem itself, which means to develop strategies to answer the questions:

Why antibiotic resistance, which is known since a century, it’s a problem on the rise?

What is the role and interest of capitalism, in terms of profit-making of corporations, knowledge production and environmental degradation, in not being able to resolve antibiotic resistance?

What can be strategies of local communities to tackle the problem and to promote environmental justice in terms of alliances with ecologists, doctors, epidemiologists and other activists?

pece_annotation_1524443970

stephanie.niev…

After the storms, many towns affected came up with ways to increase protection in infrastructure. Town officials working alongside exerpts have been working to upgrade their plans on making their communities more resilient to natural disasters. There have also many several funds and donations for the towns affected by Sandy; there have also been ways on how to help prevent flooding in such areas. In the article, it discusses how "the DEP has worked with local officials to design a proposed $230 million federally-funded system of flood walls along the Hudson River for Hoboken and parts of Weehawken and Jersey City."

 

pece_annotation_1524446324

stephanie.niev…

"Hurricane Irene marches north, leaving at least 8 people dead and close to 2 million without power in the states it has already hit. Tonight it bore down on millions more from the Delmarva peninsula to the Jersey Shore and the New York metropolitan area."

"More than a million residents and visitors of the Jersey Shore have been evacuated, though a stubborn 600 people, many of them senior citizens, remain in high rise buildings on a barrier island in Atlantic City, according to New Jersey Gov. Chris Christie. Even before the core of the hurricane reached the area Sunday, Christie said winds could reach up to 75 mph at the upper floors of some of the buildings."

"New York Gov. Andrew Cuomo ordered 2,000 National Guard troops deployed to Long Island, New York City, and the Hudson Valley area to help with the storm. Troops will help staff shelters, control evacuation routes, monitor flood threats at the World Trade Center site and work with the Metropolitan Transportation Authority to secure railways and train tunnels."

"Defense Secretary Leon Panetta has issued a prepare-to-deploy order for 6,500 active duty troops from all the services to support hurricane relief efforts if necessary."

pece_annotation_1524443656

stephanie.niev…

The aftermaths of Sandy had created many vulnerabilites to the communities around the shores. There were about 840 million gallons of raw sewage scattered into the Passaic River; and since the sewerage system had struggled to get back to full operating hours and service, there were 4.4 billion gallons of partially treated sewage were released into New York Harbor. In addition, many infrastructure was severely damaged after the storm: houses, power substations, police headquarters, etc.

 

pece_annotation_1517362310

stephanie.niev…

The main sources of resilience are: discussing the list of pollutants that are spread across through a demographic structure, how pollutants affect and become more apparent to different race and economic levels; the information about possible new pollutants that could appear due to the addition of new companies; and the reconstruction on the zoning laws in Newark. Additionally, there are numerous environmentalists of all types behind this new addition to the zoning and land use regulations. 

pece_annotation_1524445686

stephanie.niev…

Although this article talks about how NJPAC will donate money to the victims of the natural disaster, it doesn't include how the money will be used: will it be used to help support the people affected by the storm, help rebuild the building destroyed, etc? In addition, I feel as if this article is missing the key information of how severe the storm struck some places along the coast: by providing such information, it would create more awareness and allow a higher chance for the tickets to be purchased to help support the cause.

pece_annotation_1524594757

ArielMejiaNJIT
Annotation of

I uploaded this artifact because I believe that reparing Newark’s infrastructure is very important, especially since a lot of it’s economy relies on it. Without the repairs, it would lead to bigger problems such as increasing the cost of maintenance for its residents and the companies that use it daily. This decision made me realize that although Newark is struggling in bringing its economy back, its politicians know that maintaining it’s road is the foundation towards recovering from the recession.

pece_annotation_1524447454

stephanie.niev…

In the article, it expalins the various attempts of securing the area and preventing further damage from the storm. There were several plans of evacuation, shelters opened up to those in need, protection of federal troops were deployed and many towns offered relief help after the storm had passed.

pece_annotation_1524443310

stephanie.niev…

The most resilience the beaches and the communities around the shores have are federal aid. There have been numerous plans and discussions on how to help reconstruct the shores of New Jersey. In addition, several Congress members and even the vice president at the time, Joe Biden, showed their want to help aid in the recovery of natural disasters.