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The narrative is sustained through emotional stories of end of life care from both the physician and patient perspectives performed by both Dr. Atul Gawande and by other healthcare professionals such as oncologists, palliative care experts, other surgeons. The scientific background of end of life care isn't really discussed in detail, as this film focuses more on the social and emotional aspects of this topic.

According to its mission statement, "The American Red Cross prevents and alleviates human suffering in the face of emergencies by mobilizing the power of volunteers and the generosity of donors.​"