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"Antibiotic Resistance in Louisiana"

fdabramo

I situate my research at the crossroads of history, philosophy, sociology and anthropology of science. In the past, I have focused on epigenetics, environmental research, empirical bioethics and environmental justice, within and outside the academia, as you can read here, or here. Now I am focusing on antibiotic resistance, and I use it as a lens to interpret the contradictions of the last century derived by industrial production, environmental degradation and biomedical cultures.

What interests me is the (at that time) new epistemic discourse that since the Forties has been produced to explain morphological changes of organisms produce when they experience new environmental conditions or perturbations. Through an important experiment at the base of the so-called concept of genetic assimilation, Conrad H. Waddington showed that a thermic shock can produce changes in wings’ veins of fruit flies, changes that can eventually be inherited across generations, without the environmental trigger that caused them.

This focus on production and (genetic) storage of biological differences elicited by the environment is nowadays coupled with the knowledge produced through microbiome research that explains the phenotypic patterns that recur across generations.

In a thought-provoking twist, with microbiome research, the focus shifts from production and inheritance of biological differences to production and inheritance of biological similarities. Microbiome research shows that some phenotypic patterns are allowed by ecological communities of microorganisms composing all animals. Bacteria allow the development and functioning of our bodies within an epistemic framework that is now key to understand biology. The network of vessels composing mammals’ stomach is formed through cellular differentiation and expression of genes coordinated by bacteria. The same is true for our immune system that is coordinated by gut bacteria. Food, which is an important aspect of our lives also impacts on this microecology and mediates between our biological functions and functioning of means of production whose parts dedicated to food production have immense importance for our biology and our internal and external ecologies. Antibiotic resistance is one of the crossroads where culture, biology, history and the Anthropocene meet. Indeed, Antibiotic resistance shows that means of production of our societies have an even more widespread, deep and allegedly unexpected impact on the biology of animals and plants. The microorganism can indeed adapt to resist the selective toxicity of antibiotics. Moreover, bacteria can transfer their genetic code horizontally, by touch, so that we can acquire antibiotic resistance by eating food that functions as a vector, by hosting lice on our heads and many other contacts. Bacteria that are resistant to antibiotics that have been used as growth factors in animal husbandry and to prevent diseases in livestock and aquaculture, spread in natural ecosystems and can be found in wild species. Rivers and estuarine waters are places hosting antibiotic resistance.

Searching on PubMed (the search engine for biomedical literature) titles of articles containing the terms ‘antimicrobial’ and ‘Louisiana’ I retrieved just one twelve-years-old article. No results with terms such as 'Mississippi' or 'New Orleans'. The authors collected and analysed Oysters from both waters of Louisiana Gulf and in restaurants and food retailers in Baton Rouge. In most of the samples gathered, scientists recognised the presence of bacteria (Vibrio parahaemolyticus and Vibrio vulnificus) resistant to specific antimicrobials. Food production is indeed the first factor in terms of the quantity of antibiotics used. This use and related antibiotic resistance impact all the living beings present in a specific area, and can easily travel around the globe through many channels. As Littman & Viens have highlighted, a sustainable future is a future without antibiotics as “there may be no truly sustainable way of using antibiotics in the long-run, as microorganisms have shown to be almost infinitely adaptable since the first introduction of antibiotics” (Littman & Viens 2015). But in the meanwhile, we need to use them and antibiotic resistance is a phenomenon that can be better studied through environmental research, by analysing wild species and emissions nearby livestock, for instance.

The study that I retrieved focuses on Oysters. But what about antibiotic resistance conveyed through food that is consumed by the most?

What about exposures of communities that are living in highly polluted areas?

And what is the additive value on antibiotic resistance for individuals who experience the presence of industrial pollutants and that live in areas where cancer epidemics are registered?

In this respect, there is a strategy to cope with the issue of antibiotic resistance promoted by the Center for Disease Control and Prevention. The document doesn’t mention any action to monitor and regulate the production and usage of antibiotics in livestock. Nevertheless, the CDC wants to scrutinise, through genome sequencing, “Listeria, Salmonella, Campylobacter, and E. coli and uploads sequence data into PulseNet for nationwide monitoring of outbreaks and trends.” Moreover, the document reports that “In Fiscal Year 2019, Louisiana will begin simultaneously monitoring these isolates for resistance genes. When outbreaks are detected, local CDC-supported epidemiologists investigate the cases to stop spread.”

The questions that I would like to ask (to local ppl, activists, researchers, practitioners..) are:

What could be the epidemiologic characteristics (socioeconomic status, gender, residence..) of the populations more vulnerable to antibiotic resistance?

What is the additive role of antibiotic resistance for people living in highly polluted areas?

What is the impact of antibiotic resistance for people and patients living in areas where cancer incidence is high?

 

And on the long run I am interested in imagining possible strategies to not only living with the problem but also to tackle the problem itself, which means to develop strategies to answer the questions:

Why antibiotic resistance, which is known since a century, it’s a problem on the rise?

What is the role and interest of capitalism, in terms of profit-making of corporations, knowledge production and environmental degradation, in not being able to resolve antibiotic resistance?

What can be strategies of local communities to tackle the problem and to promote environmental justice in terms of alliances with ecologists, doctors, epidemiologists and other activists?

1619 Project

ramah

This may not be the right place to post/share this, and I am happy to delete or move it! But I wanted to make a plug for the 1619 Project, and this post in particular, as helpfully complementing some of the other readings (such as McKittrick and Moore et al) on America's plantation history.

https://www.nytimes.com/interactive/2019/08/14/magazine/slavery-capital…

Hazardous waste work, race, and making disaster "professions"

ramah
I began my research for these field notes by thinking about what kind of labor becomes available in the context of disaster relief/climate change? In my teaching this week, I have been talking about Cyclone Idai and mold as an example of one of how disasters unfold over different temporalities, as in Kim’s work, and via ‘aftershocks’ (Bonilla and Lebron 2019). Thinking about mold got me googling respiratory infections/respiratory health in New Orleans, which lead me to various sites that offer hazardous waste worker training programs (including under the auspices of environmental justice/community development work - e.g. http://www.dscej.org/our-work). This seems one example, among others, of how exposure to environmental harm is transformed into new sites of professionalization. This called to mind discussions of risky labor in the context of disaster, such as in Fortun 2001 or Petryna 2002, and to the centrality of respiration to thinking about anthropocenic processes (Kenner 2019). It highlighted how that transformation of geographical exposure into professional opportunity is then refracted via race and class; while some become hazardous waste clean up experts, others become climate change experts and professionals, who deploy expertise in the wake of other storms. Other accounts (https://blog.nationalgeographic.org/2018/03/06/meet-the-refugees-fighting-for-the-future-of-new-orleans/) highlighted specific communities, such as refugee communities, as key sites of resistance to energy infrastructures including a new gas plant, which is being constructed in a FEMA-designated high-risk flood zone. This short stint of googling also lead me to a number of studies of respiratory health, many using spirometric readings to calculate the impact of exposure (for instance to remediation workers involved in cleaning after Hurricane Katrina) (eg. Rando et al 2012). Having recently read Lundy Braun’s book about race and spirometry (2014), these accounts highlighted for me how racialization is built into these processes in multiple ways: not only does race (along with class, professional background, geographical situation, etc) shape who is exposed and in what ways, it also shapes the how health and harm are measured and made visible in this context.Reference:Rando, Roy, John Lefante, Laurie Freyder, & Robert Jones. 2012. Journal of Environmental and Public Health. https://www.hindawi.com/journals/jeph/2012/462478/

Where/whether to place human mobility in thinking anthropocenically

ramah
Is there a place for thinking about the relationship between the governance of human mobility and anthropogenic processes in Louisiana? Reading the Andy Horowitz piece about Hurricane Harvey and the McKittrick piece about plantations got me thinking about the governance of human mobility as central to how New Orleans, and especially storms, are narrated. The ways in which mobility is made possible or impeded are central to ’storm narratives’. At the same time, recent news has highlighted how ICE activities have been concentrated in Mississippi, Louisiana, and other parts of the South. As the Southern Poverty Law Center notes, "The South is both a destination for new immigrants seeking security in the U.S. and a staging ground for deportation.” Louisiana - although perhaps not New Orleans - seems to be a key site in which these processes are visible. For instance, a report on NBC suggested that, “the number of detainees in facilities contracted by Immigration and Customs Enforcement in Louisiana and Mississippi surged from just over 2,000 at the end of 2017 to more than 8,000 as of July. That’s nearly four times as many as were detained in the two states in November 2017, the numbers show. Louisiana, with a population of more than 6,500, now has the largest population of ICE detainees of any single state apart from Texas.” One reason for this increase in numbers is financial. According to the SPLC, "The South, which already has some of the highest rates of incarceration in the country, is the bargain basement of immigration detention. Facilities charge among the lowest per diem rates in the country in order to land Immigration and Customs Enforcement (ICE) contracts that can create jobs for communities, revenue for municipalities and profits for private prison operators, no matter the long-term cost. It’s an approach that flows from the South’s long history of looking to prisons filled mostly with people of color as a way to build local economies – a history that includes chain gangs and programs that “leased” prisoners to companies for work. Today, immigrant detention is but the latest chapter in that history” https://www.splcenter.org/20161121/shadow-prisons-immigrant-detention-south). Yet as this quote suggests, this mode of detention is also historical, and that history seems to play out in a number of ways. Facilities used to detain migrants have often also been used as prisons (including the La Salle detention center in Jena, Louisiana), for instance. But it seems that tensions around the notion of New Orleans as a "city of refuge” (Munyikwa 2019) are long-standing. Even as today, the Southern Poverty Law Center reports highlighted Cuban immigrants/asylum seekers, so too are tensions over racialized Caribbean migration longstanding. In the aftermath of the Haitian revolution, New Orleans was a kind of “flashpoint” (Kazanjian 2003) for tensions over migration and race as both French settlers from Haiti fled to Louisiana and as Afro-Creole refugees were expelled from Cuba. One report of the 1809 migration describes how “in Louisiana, as lawmakers moved to suppress manumission and undermine the free black presence, the refugees dealt a serious blow to their efforts.” http://www.inmotionaame.org/migrations/topic.cfm;jsessionid=f8302584551566978728483?migration=5&topic=3&bhcp=1 These are all clumsy linkages, and I’m not sure I want to draw historical analogies across contexts about which I have only cursory knowledge, but it seems to me that there are linkages or repetitions of connections between labor, environment, and human mobility that for me provoke questions about the relationship between anthropocenics and regimes of human mobility and carcerality (beyond just the notion of ‘climate refugees’). Resources consulted: https://www.nbcnews.com/politics/immigration/ice-detainments-surge-mississippi-louisiana-alarming-immigration-advocates-n1042696 Southern Poverty Law Center & National Lawyers’ Guildhttps://www.splcenter.org/20161121/shadow-prisons-immigrant-detention-southhttps://www.splcenter.org/news/2019/04/10/cuban-men-thrown-louisiana-prisons-despite-legal-asylum-requests http://www.inmotionaame.org/migrations/topic.cfm;jsessionid=f8302584551566978728483?migration=5&topic=3&bhcp=1 https://www.theadvocate.com/gambit/new_orleans/news/the_latest/article_8687dfba-a127-5bb9-9635-25502c2916dc.html https://nolapsc.org/human-rights/ Munyikwa, Michelle. 2019. ‘Up from the dirt’: Racializing Refuge, Rupture, and Repair in Philadelphia. Dissertation submitted to the Department of Anthropology, University of Pennsylvania. 

Creating a mobile disaster industry

ramah
I haven’t gone as deeply into this as I’d like, but I started by trying to find out which private firms/actors were associated with disaster response in the wake of Hurricane Katrina (beyond the groups, like Blackwater, that made headlines). What I actually found was the way in which New Orleans- and Louisiana-based firms and individuals are positioning themselves as disaster experts (or, as seems to be the preferred language, experts in resiliency and preparedness) in the wake of Katrina and subsequent storms (e.g. Isaac). So, groups involved in the initial response include companies like Beck Disaster Relief, AshBritt, Shaw Group, Korte, Fluor, Halliburton spin-offs, and Akima site contractors, but these groups have also used Katrina to position themselves or consolidate their position as disaster relief specialists. Other organizations, like Greater New Orleans Inc (GNO), Royal Engineers, Hammerman and Garner International and others, expanded from local contracting or civic bodies to national or international actors, as experience navigating not only the material landscape of Katrina but also the bureaucratic and financial landscape of FEMA became a selling point for further projects — for instance, many of these organizations went on to bid for public contracts in the aftermath of Hurricane Sandy and subsequent preparedness activities. If these firms point to a genealogy of expertise spooling forward from Katrina, there are also financial genealogies that predate the privatized response to Katrina — for instance, the way Housing and Urban Development’s community development block grants (CDBGs), originally designed to promote “urban revitalization” became used as disaster relief funds. I also have not included here the key role played by humanitarian agencies and NGOs, both nationally and overseas.The other way I’ve been preparing for the Field Campus is by thinking about the stakes of claiming - in my own work or in the work of these firms - New Orleans (and especially a mass-mediated event like Katrina) as a site for authorizing and producing knowledge. To that end, thinking with Christina Sharpe’s In the Wake, Katherine McKittrick’s Demonic Grounds, and Tina Campt’s work on refusal has been helpful, since these authors are concerned in part with how the hypervisibility of Black suffering underpins so much of American political life, and locate Katrina as part of that; those texts are helping me to start thinking about what possible starting points for my thinking might exist in relation to this analytical/geographical/empirical anthropocenic space.Some media accounts and reports:https://www.motherjones.com/environment/2009/08/secret-history-hurricane-katrina/https://corpwatch.org/article/katrina-contractors-rake-it-they-clean-ithttps://iem.comhttps://www.nola.gov/community-development/documents/isaac-recovery-program/action-plan-amendments/cno-isaac-action-plan-amend-1/https://capitalresearch.org/article/private-sector-disaster-relief/https://resconnola.com

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maryclare.crochiere
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The organization has workers that live in the various communities to increase trust with the native people, and show them that the nurses and midwives are there to help and save lives, not take over. They do home visits since travel is hard in many of the areas, and they do routine check ups to make sure that clean water and living conditions are aiding recovery processes apporopriately.

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maryclare.crochiere

There are four regions of microbial threats that the paper focuses on: emerging infectious disease; bioterrorism; life sciences; and food safety.

Huge increases on spending in the US on biodefense from millions to billions of dollars

Very general emergency response plans have weaknesses in that they are so quickly applied to any situation without considering what a specific region needs, has, or lacks.

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maryclare.crochiere

The real threats of air quality were covered up due to politics and other reasons, wanting to get america back to work. Instead, the reports were edited and people were sent back into the dirty air to clean up the scene or back to office jobs in the area, with contaminated air surrounding everything. Decontanimation efforts did not start until very late in the process. Bush did not wear a mask and the workers were told they didn't need to, so they didn't. As a result, there were severe health problems afterwards.

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maryclare.crochiere

It was created to further outline the uses and resposibilities of medicaid, specifically with IMDs. It places more responsibility on the states for middle-aged people in need of this type of care, rather than the federal government. These changes and specifications occurred throughout the 1970's and 80's, when mental health was becoming more of an understood issue, and treatment of those with mental diseases was being improved.