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I situate my research at the crossroads of history, philosophy, sociology and anthropology of science. In the past, I have focused on epigenetics, environmental research, empirical bioethics and environmental justice, within and outside the academia, as you can read here, or here. Now I am focusing on antibiotic resistance, and I use it as a lens to interpret the contradictions of the last century derived by industrial production, environmental degradation and biomedical cultures.

What interests me is the (at that time) new epistemic discourse that since the Forties has been produced to explain morphological changes of organisms produce when they experience new environmental conditions or perturbations. Through an important experiment at the base of the so-called concept of genetic assimilation, Conrad H. Waddington showed that a thermic shock can produce changes in wings’ veins of fruit flies, changes that can eventually be inherited across generations, without the environmental trigger that caused them.

This focus on production and (genetic) storage of biological differences elicited by the environment is nowadays coupled with the knowledge produced through microbiome research that explains the phenotypic patterns that recur across generations.

In a thought-provoking twist, with microbiome research, the focus shifts from production and inheritance of biological differences to production and inheritance of biological similarities. Microbiome research shows that some phenotypic patterns are allowed by ecological communities of microorganisms composing all animals. Bacteria allow the development and functioning of our bodies within an epistemic framework that is now key to understand biology. The network of vessels composing mammals’ stomach is formed through cellular differentiation and expression of genes coordinated by bacteria. The same is true for our immune system that is coordinated by gut bacteria. Food, which is an important aspect of our lives also impacts on this microecology and mediates between our biological functions and functioning of means of production whose parts dedicated to food production have immense importance for our biology and our internal and external ecologies. Antibiotic resistance is one of the crossroads where culture, biology, history and the Anthropocene meet. Indeed, Antibiotic resistance shows that means of production of our societies have an even more widespread, deep and allegedly unexpected impact on the biology of animals and plants. The microorganism can indeed adapt to resist the selective toxicity of antibiotics. Moreover, bacteria can transfer their genetic code horizontally, by touch, so that we can acquire antibiotic resistance by eating food that functions as a vector, by hosting lice on our heads and many other contacts. Bacteria that are resistant to antibiotics that have been used as growth factors in animal husbandry and to prevent diseases in livestock and aquaculture, spread in natural ecosystems and can be found in wild species. Rivers and estuarine waters are places hosting antibiotic resistance.

Searching on PubMed (the search engine for biomedical literature) titles of articles containing the terms ‘antimicrobial’ and ‘Louisiana’ I retrieved just one twelve-years-old article. No results with terms such as 'Mississippi' or 'New Orleans'. The authors collected and analysed Oysters from both waters of Louisiana Gulf and in restaurants and food retailers in Baton Rouge. In most of the samples gathered, scientists recognised the presence of bacteria (Vibrio parahaemolyticus and Vibrio vulnificus) resistant to specific antimicrobials. Food production is indeed the first factor in terms of the quantity of antibiotics used. This use and related antibiotic resistance impact all the living beings present in a specific area, and can easily travel around the globe through many channels. As Littman & Viens have highlighted, a sustainable future is a future without antibiotics as “there may be no truly sustainable way of using antibiotics in the long-run, as microorganisms have shown to be almost infinitely adaptable since the first introduction of antibiotics” (Littman & Viens 2015). But in the meanwhile, we need to use them and antibiotic resistance is a phenomenon that can be better studied through environmental research, by analysing wild species and emissions nearby livestock, for instance.

The study that I retrieved focuses on Oysters. But what about antibiotic resistance conveyed through food that is consumed by the most?

What about exposures of communities that are living in highly polluted areas?

And what is the additive value on antibiotic resistance for individuals who experience the presence of industrial pollutants and that live in areas where cancer epidemics are registered?

In this respect, there is a strategy to cope with the issue of antibiotic resistance promoted by the Center for Disease Control and Prevention. The document doesn’t mention any action to monitor and regulate the production and usage of antibiotics in livestock. Nevertheless, the CDC wants to scrutinise, through genome sequencing, “Listeria, Salmonella, Campylobacter, and E. coli and uploads sequence data into PulseNet for nationwide monitoring of outbreaks and trends.” Moreover, the document reports that “In Fiscal Year 2019, Louisiana will begin simultaneously monitoring these isolates for resistance genes. When outbreaks are detected, local CDC-supported epidemiologists investigate the cases to stop spread.”

The questions that I would like to ask (to local ppl, activists, researchers, practitioners..) are:

What could be the epidemiologic characteristics (socioeconomic status, gender, residence..) of the populations more vulnerable to antibiotic resistance?

What is the additive role of antibiotic resistance for people living in highly polluted areas?

What is the impact of antibiotic resistance for people and patients living in areas where cancer incidence is high?

And on the long run I am interested in imagining possible strategies to not only living with the problem but also to tackle the problem itself, which means to develop strategies to answer the questions:

Why antibiotic resistance, which is known since a century, it’s a problem on the rise?

What is the role and interest of capitalism, in terms of profit-making of corporations, knowledge production and environmental degradation, in not being able to resolve antibiotic resistance?

What can be strategies of local communities to tackle the problem and to promote environmental justice in terms of alliances with ecologists, doctors, epidemiologists and other activists?

The Burning of the US Capitol Building, 1814. From the very beginnings of its contruction, the US Capitol Building was plagued by conflict between the chief engineer Benjamin Henry Latrobe, who desired a durable and fireproof design, and Congress, which pushed for rapid completion of the building with limited expense. The result was a mixed contruction, with parts of the building constructed to withstand a major fire and others constructed with lumber. Following the fire, Latrobe conducted a relatively thorough investigation, revealing the various points of failure and recontructing the timeline of the disaster. However, as far as the public was concerned, the disaster was the result of diplomatic and military failures, rather than any engineering failures. 

The Hague Street Explosion, 1850. Steam power was widely used in the United States, but safety protocols and standards were not widespread nor maintained by any particular agency. The exact nature and cause of the boiler explosion at Hague Street was widely debated by various experts, engineers, and laypersons. The federal government scrambled to enact new laws regarding boiler inspection and safety with little effect in reducing boiler-related disasters, while city officials instead chose to remember the disaster through a fund-raising campaign for the victims' families. 

The Iroquois Theater Fire in Chicago, 1903. The disaster called into question the integrity of the building code system in the city of Chicago and caused widespread debate regarding who should be responsible for enforcing building codes. The disaster resulted in a rapid expansion of fire code and fire safety standards and the creation of a network of investigators, comprised of engineers, insurance agencies, testing labs, and fire officials. However, the pressure for such action and progress soon declined as the government, press, and public moved on from the disaster. 

This policy affects all patients, or potential patients, in the United States and further affects all hospitals and care providers. It ensures that all patients suffering from emergency medical condition(s) are provided the appropriate medical care regardless of their initial ability to pay. Furthermore, it requires that hospitals, their emergency departments, and their staff must treat and stabilize these patients prior to transferring to another facility. 

• "Chronic disaster syndrome thus refers in this analysis to the cluster of trauma-and posttrauma-related phenomena that are at once individual, social, and political and that are associated with disaster as simultaneously causative and experiential of a chronic condition of distress in relation to displacement."
• "Despite the overwhelming need for mental health services, few residents were able to access mental health support for their symptoms, simply because health care facilities and health care personnel were so scarce. Most health personnel were themselves experiencing the trauma of displacement, and few clinical facilities survived the disaster."
• "Families had to find a place to live, a way to replace lost income, a place for their children to go to school, a way to obtain their prescription medications and telephones, a way to pay mounting unpaid bills for homes they no longer inhabited. Without their personal documents, they had to try to track insurance policies, if they had them, bank accounts, and health records, to begin the slow process of accessing government or insurance funds to help pay for their displacement and their hoped-for recovery."

The Cold War was a principal motivating factor for the IPPNW who aims to abolish nuclear weapons and thereby prevent nuclear war and destruction.

The authors present the issues surrounding increasing violence against healthcare professionals, especially in regions where the geopolitical or socioeconomic conditions have created environments with lack of security. One major issue cited is the lack of ongoing research into these issues.

The authors present the modernization and globalization of nations and the emerging global threat of infectious diseases as the primary catalysts for the intersection of various organizations concerned with biosecurity and public health. Numerous national and multi-national organizations have reacted to this emerging threat by developing new strategic frameworks to promote prevention and preparedness. The increase in tension among various organizations on developing effective strategies is indicative of the overlapping fields of national security, biosecurity, public safety, and global health. 

The primary responsibility of the Occupational Safety and Health Administration (OSHA) is "...to assure safe and healthful working conditions for working men and women by setting and enforcing standards and by providing training, outreach, education and assistance." The mission is to improve the safety and health of workers in all industries.