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I situate my research at the crossroads of history, philosophy, sociology and anthropology of science. In the past, I have focused on epigenetics, environmental research, empirical bioethics and environmental justice, within and outside the academia, as you can read here, or here. Now I am focusing on antibiotic resistance, and I use it as a lens to interpret the contradictions of the last century derived by industrial production, environmental degradation and biomedical cultures.

What interests me is the (at that time) new epistemic discourse that since the Forties has been produced to explain morphological changes of organisms produce when they experience new environmental conditions or perturbations. Through an important experiment at the base of the so-called concept of genetic assimilation, Conrad H. Waddington showed that a thermic shock can produce changes in wings’ veins of fruit flies, changes that can eventually be inherited across generations, without the environmental trigger that caused them.

This focus on production and (genetic) storage of biological differences elicited by the environment is nowadays coupled with the knowledge produced through microbiome research that explains the phenotypic patterns that recur across generations.

In a thought-provoking twist, with microbiome research, the focus shifts from production and inheritance of biological differences to production and inheritance of biological similarities. Microbiome research shows that some phenotypic patterns are allowed by ecological communities of microorganisms composing all animals. Bacteria allow the development and functioning of our bodies within an epistemic framework that is now key to understand biology. The network of vessels composing mammals’ stomach is formed through cellular differentiation and expression of genes coordinated by bacteria. The same is true for our immune system that is coordinated by gut bacteria. Food, which is an important aspect of our lives also impacts on this microecology and mediates between our biological functions and functioning of means of production whose parts dedicated to food production have immense importance for our biology and our internal and external ecologies. Antibiotic resistance is one of the crossroads where culture, biology, history and the Anthropocene meet. Indeed, Antibiotic resistance shows that means of production of our societies have an even more widespread, deep and allegedly unexpected impact on the biology of animals and plants. The microorganism can indeed adapt to resist the selective toxicity of antibiotics. Moreover, bacteria can transfer their genetic code horizontally, by touch, so that we can acquire antibiotic resistance by eating food that functions as a vector, by hosting lice on our heads and many other contacts. Bacteria that are resistant to antibiotics that have been used as growth factors in animal husbandry and to prevent diseases in livestock and aquaculture, spread in natural ecosystems and can be found in wild species. Rivers and estuarine waters are places hosting antibiotic resistance.

Searching on PubMed (the search engine for biomedical literature) titles of articles containing the terms ‘antimicrobial’ and ‘Louisiana’ I retrieved just one twelve-years-old article. No results with terms such as 'Mississippi' or 'New Orleans'. The authors collected and analysed Oysters from both waters of Louisiana Gulf and in restaurants and food retailers in Baton Rouge. In most of the samples gathered, scientists recognised the presence of bacteria (Vibrio parahaemolyticus and Vibrio vulnificus) resistant to specific antimicrobials. Food production is indeed the first factor in terms of the quantity of antibiotics used. This use and related antibiotic resistance impact all the living beings present in a specific area, and can easily travel around the globe through many channels. As Littman & Viens have highlighted, a sustainable future is a future without antibiotics as “there may be no truly sustainable way of using antibiotics in the long-run, as microorganisms have shown to be almost infinitely adaptable since the first introduction of antibiotics” (Littman & Viens 2015). But in the meanwhile, we need to use them and antibiotic resistance is a phenomenon that can be better studied through environmental research, by analysing wild species and emissions nearby livestock, for instance.

The study that I retrieved focuses on Oysters. But what about antibiotic resistance conveyed through food that is consumed by the most?

What about exposures of communities that are living in highly polluted areas?

And what is the additive value on antibiotic resistance for individuals who experience the presence of industrial pollutants and that live in areas where cancer epidemics are registered?

In this respect, there is a strategy to cope with the issue of antibiotic resistance promoted by the Center for Disease Control and Prevention. The document doesn’t mention any action to monitor and regulate the production and usage of antibiotics in livestock. Nevertheless, the CDC wants to scrutinise, through genome sequencing, “Listeria, Salmonella, Campylobacter, and E. coli and uploads sequence data into PulseNet for nationwide monitoring of outbreaks and trends.” Moreover, the document reports that “In Fiscal Year 2019, Louisiana will begin simultaneously monitoring these isolates for resistance genes. When outbreaks are detected, local CDC-supported epidemiologists investigate the cases to stop spread.”

The questions that I would like to ask (to local ppl, activists, researchers, practitioners..) are:

What could be the epidemiologic characteristics (socioeconomic status, gender, residence..) of the populations more vulnerable to antibiotic resistance?

What is the additive role of antibiotic resistance for people living in highly polluted areas?

What is the impact of antibiotic resistance for people and patients living in areas where cancer incidence is high?

And on the long run I am interested in imagining possible strategies to not only living with the problem but also to tackle the problem itself, which means to develop strategies to answer the questions:

Why antibiotic resistance, which is known since a century, it’s a problem on the rise?

What is the role and interest of capitalism, in terms of profit-making of corporations, knowledge production and environmental degradation, in not being able to resolve antibiotic resistance?

What can be strategies of local communities to tackle the problem and to promote environmental justice in terms of alliances with ecologists, doctors, epidemiologists and other activists?

"The violence broke out when the patient spit at the Emergency Service Unit officers and swore at them. The officers responded by hitting him in the face, hauling him off the stretcher to the ground and then tossing him back on the stretcher, the EMTs said in written statements submitted to the FDNY."

""Three cops began to punch the patient in the face, EMS (had) to get in the middle of it to intervene. Pt's. wounds and injuries cleaned in the (ambulance)," the report said"

Dr. Peter Kramer- a clinical professor of psychiatry at Brown University. Author of the article. 

This is a program targeted to students with bachelors, masters, or professional degrees who desire to protect people from the various consequences of nuclear disasters. 

The information used to produce and support the arguments made in the article comes from a number of articles and reports, as well as interviews. For example, the author communicated with the former scientific director of Spetsatom and used that information to form a better image of the situation post-Chernobyl. This information could then be contrasted to other disasters and the organizations formed in the aftermath. The author could then use research papers as a source for statistical data, as well as scientific reports as a basis for the disaster’s existence and its implications. These all together are used to form an interdisciplinary view of disaster relief, and the steps needed to prevent and respond to another nuclear disaster.

The largest challenge faced by the ARC seems to be organizing such a large group of volunteers for specific response. There are so many different pieces to disaster respones, and with mostly volunteers organizing things, a strong central leadership is needed, which seems to be lacking in the group as a whole. 

The rise and emergence of infectious diseases has led to a number of puclic health "scares" over the years. The creation of national and international frameworks, as well as focus groups, has brought the struggle of infectious diseases like AIDS to light. Looking at diseases with the combined inputs of governmental and philanthropic organizations has had a positive influence on the fight against them. In the realm of bioterrorism, many factors are at play. First is the terrorist act itself and the social issues that lead to a terrorist being created. Then there is themethod, which is the numerous diseases that can be weaponized. These diseases are researched at the government level as potential additions to the arsenal of weapons a country has. However, they are also used at the individual level. With highly educated individuals and any number of social ideologies, the risk for bioterrorism increases. By looking at bioterrorism through the lens of both a social expert and scientist, the roots of bioterrorism can be examined. 

The causes for these examinations are events that have had a largescale effect on multiple levels of expertise. These "focusing events" have a lot of factors and players, and thus require a lot of different views to analyze, as the article argues. 

Emergency responders as a unique group aren't discussed or portrated in the film. However, the doctors had to take on the role of emergency responders often, while not neccesarily being emergency doctors. The question in the film became whether or not the doctors were prepared for these roles, and if they had the energy to dedicate to them. Some doctors burn out, and others thrive, but regardless they are challenged to make sacrifices that emergency responders often must decide on.