Skip to main content

Search

"Antibiotic Resistance in Louisiana"

fdabramo

I situate my research at the crossroads of history, philosophy, sociology and anthropology of science. In the past, I have focused on epigenetics, environmental research, empirical bioethics and environmental justice, within and outside the academia, as you can read here, or here. Now I am focusing on antibiotic resistance, and I use it as a lens to interpret the contradictions of the last century derived by industrial production, environmental degradation and biomedical cultures.

What interests me is the (at that time) new epistemic discourse that since the Forties has been produced to explain morphological changes of organisms produce when they experience new environmental conditions or perturbations. Through an important experiment at the base of the so-called concept of genetic assimilation, Conrad H. Waddington showed that a thermic shock can produce changes in wings’ veins of fruit flies, changes that can eventually be inherited across generations, without the environmental trigger that caused them.

This focus on production and (genetic) storage of biological differences elicited by the environment is nowadays coupled with the knowledge produced through microbiome research that explains the phenotypic patterns that recur across generations.

In a thought-provoking twist, with microbiome research, the focus shifts from production and inheritance of biological differences to production and inheritance of biological similarities. Microbiome research shows that some phenotypic patterns are allowed by ecological communities of microorganisms composing all animals. Bacteria allow the development and functioning of our bodies within an epistemic framework that is now key to understand biology. The network of vessels composing mammals’ stomach is formed through cellular differentiation and expression of genes coordinated by bacteria. The same is true for our immune system that is coordinated by gut bacteria. Food, which is an important aspect of our lives also impacts on this microecology and mediates between our biological functions and functioning of means of production whose parts dedicated to food production have immense importance for our biology and our internal and external ecologies. Antibiotic resistance is one of the crossroads where culture, biology, history and the Anthropocene meet. Indeed, Antibiotic resistance shows that means of production of our societies have an even more widespread, deep and allegedly unexpected impact on the biology of animals and plants. The microorganism can indeed adapt to resist the selective toxicity of antibiotics. Moreover, bacteria can transfer their genetic code horizontally, by touch, so that we can acquire antibiotic resistance by eating food that functions as a vector, by hosting lice on our heads and many other contacts. Bacteria that are resistant to antibiotics that have been used as growth factors in animal husbandry and to prevent diseases in livestock and aquaculture, spread in natural ecosystems and can be found in wild species. Rivers and estuarine waters are places hosting antibiotic resistance.

Searching on PubMed (the search engine for biomedical literature) titles of articles containing the terms ‘antimicrobial’ and ‘Louisiana’ I retrieved just one twelve-years-old article. No results with terms such as 'Mississippi' or 'New Orleans'. The authors collected and analysed Oysters from both waters of Louisiana Gulf and in restaurants and food retailers in Baton Rouge. In most of the samples gathered, scientists recognised the presence of bacteria (Vibrio parahaemolyticus and Vibrio vulnificus) resistant to specific antimicrobials. Food production is indeed the first factor in terms of the quantity of antibiotics used. This use and related antibiotic resistance impact all the living beings present in a specific area, and can easily travel around the globe through many channels. As Littman & Viens have highlighted, a sustainable future is a future without antibiotics as “there may be no truly sustainable way of using antibiotics in the long-run, as microorganisms have shown to be almost infinitely adaptable since the first introduction of antibiotics” (Littman & Viens 2015). But in the meanwhile, we need to use them and antibiotic resistance is a phenomenon that can be better studied through environmental research, by analysing wild species and emissions nearby livestock, for instance.

The study that I retrieved focuses on Oysters. But what about antibiotic resistance conveyed through food that is consumed by the most?

What about exposures of communities that are living in highly polluted areas?

And what is the additive value on antibiotic resistance for individuals who experience the presence of industrial pollutants and that live in areas where cancer epidemics are registered?

In this respect, there is a strategy to cope with the issue of antibiotic resistance promoted by the Center for Disease Control and Prevention. The document doesn’t mention any action to monitor and regulate the production and usage of antibiotics in livestock. Nevertheless, the CDC wants to scrutinise, through genome sequencing, “Listeria, Salmonella, Campylobacter, and E. coli and uploads sequence data into PulseNet for nationwide monitoring of outbreaks and trends.” Moreover, the document reports that “In Fiscal Year 2019, Louisiana will begin simultaneously monitoring these isolates for resistance genes. When outbreaks are detected, local CDC-supported epidemiologists investigate the cases to stop spread.”

The questions that I would like to ask (to local ppl, activists, researchers, practitioners..) are:

What could be the epidemiologic characteristics (socioeconomic status, gender, residence..) of the populations more vulnerable to antibiotic resistance?

What is the additive role of antibiotic resistance for people living in highly polluted areas?

What is the impact of antibiotic resistance for people and patients living in areas where cancer incidence is high?

 

And on the long run I am interested in imagining possible strategies to not only living with the problem but also to tackle the problem itself, which means to develop strategies to answer the questions:

Why antibiotic resistance, which is known since a century, it’s a problem on the rise?

What is the role and interest of capitalism, in terms of profit-making of corporations, knowledge production and environmental degradation, in not being able to resolve antibiotic resistance?

What can be strategies of local communities to tackle the problem and to promote environmental justice in terms of alliances with ecologists, doctors, epidemiologists and other activists?

Copyright Basics

Website with an excellent (and brief) explanation of fair use to copyrighted materials, along with a useful fair-use checklist that can be used to assist in fair-use analysis.

pece_annotation_1478543830

Sara.Till

The article centers on how social and political factors effected access to care for citizens in the wake of the Chernobyl nuclear disaster. Additionally, the author discusses how "at-risk" populations emerge; far too often, these populations are only noted after a disaster occurs, and are often ignored until that point. This creates a dependence on healthcare and illness for these populations, something that can be highly effected based on economic and social status. The author also discusses how technologies and government involvement dictated the situation post-disaster, and includes extensive information from resettled families and workers exposed to radiation

pece_annotation_1479066991

Sara.Till

The bibliography is not included in the PDF uploaded, most likely because this a chapter excerpt from a larger work. However, there are several citations within the article, most of which are elaborated on. These descriptions indicate the works follow similar lines of thought and provide similar information to supplement Dr. Good's assertions. This includes his description of Dr. Evelyn A. Early's works (discussed earlier--ha), and several other prominent medical anthropologists. 

pece_annotation_1480275070

Sara.Till

1) MSF policy on neutrality: One of the main aspects of humanitarian aid is to remain removed in the conflict at hand, thus assuring unbiased help towards all individuals involved. This comes from neutrality, a tenant stating that MSF and other humanitarian agencies working under MSF will not "pick" or join one side of the conflict nor will they grant a side an advantage. 

2)MSF operations head arrest: At the time of the Sudanese conflict, the Dutch branch of MSF released a report decrying the severe sexual violence perpetrated during fighting. This, in turn, led to the imprisonment and charging of MSF head of mission, Paul Foreman. The MSF report was read in the 2005 Annual International General Assembly, entailing the ongoing violence against women in the Darfur conflict in an attempt to raise awareness about the continued issue. 

3) Darfur Conflict: An major armed conflict started in 2003 with the rebellion of several liberation movements (SLM & JEM) against the Sudanese government. The violence reached a cease fire in 2010 where talks began, propagated by Doha mediators, but an agreement was never met. Thus, violence has continued through 2016, including a chemical weapon attack in September.

pece_annotation_1473618787

Sara.Till

The article discusses why, despite overwhelming amounts of foreign aid money and five years, Haiti still mimcs a disaster zone. Thousands of Haitians still live in tents and temporary housing, cholera is still raging, and rebuilding projects have stalled. The article questions why Haiti is just barely staggering back to "normal" after being given such tremendous resources. It goes on to discuss how several factors curb Haitian progress, including political turmoil and economic discord. Generally, the consensus remains (internationally) that the Haitian government cannot be entrusted money to fix these issues and must be led through the process by outside agencies. Additionally, malpractices by UN peackeeping troops have only addded to the list of problems (aka reintroducing cholera) and soured relations between Haiti and the UN.

pece_annotation_1480891762

Sara.Till

Emergency response itself is not discussed in this article; this report mostly focuses on nuances of emergency/aid worker experiences. Particularly, it centers on the sheer, inexplicable lack of information surrounding attacks, harm, obstructions, and threats experienced by health care workers.

pece_annotation_1474214328

Sara.Till

The policy applies to New York state citizens, health care workers, EMS personnel, and leadership within health care centers. Additionally, the policy has parts that effect transportation agencies and their employees. In many ways, due to Ebola's nature and the nature of New York as a major metropolitan area, these policies will also have a global effect.

pece_annotation_1474496435

Sara.Till

The article debriefs a ruling by Federal District Court Judge Deborah A. Batts on a class action lawsuit against the EPA. It details the claims made by the plantiffs' surrounding EPA officials' misconduct after 9/11. Specifically cited are Christie Whitman, who chaired the EPA  during the attacks, and several other EPA officials.