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I situate my research at the crossroads of history, philosophy, sociology and anthropology of science. In the past, I have focused on epigenetics, environmental research, empirical bioethics and environmental justice, within and outside the academia, as you can read here, or here. Now I am focusing on antibiotic resistance, and I use it as a lens to interpret the contradictions of the last century derived by industrial production, environmental degradation and biomedical cultures.

What interests me is the (at that time) new epistemic discourse that since the Forties has been produced to explain morphological changes of organisms produce when they experience new environmental conditions or perturbations. Through an important experiment at the base of the so-called concept of genetic assimilation, Conrad H. Waddington showed that a thermic shock can produce changes in wings’ veins of fruit flies, changes that can eventually be inherited across generations, without the environmental trigger that caused them.

This focus on production and (genetic) storage of biological differences elicited by the environment is nowadays coupled with the knowledge produced through microbiome research that explains the phenotypic patterns that recur across generations.

In a thought-provoking twist, with microbiome research, the focus shifts from production and inheritance of biological differences to production and inheritance of biological similarities. Microbiome research shows that some phenotypic patterns are allowed by ecological communities of microorganisms composing all animals. Bacteria allow the development and functioning of our bodies within an epistemic framework that is now key to understand biology. The network of vessels composing mammals’ stomach is formed through cellular differentiation and expression of genes coordinated by bacteria. The same is true for our immune system that is coordinated by gut bacteria. Food, which is an important aspect of our lives also impacts on this microecology and mediates between our biological functions and functioning of means of production whose parts dedicated to food production have immense importance for our biology and our internal and external ecologies. Antibiotic resistance is one of the crossroads where culture, biology, history and the Anthropocene meet. Indeed, Antibiotic resistance shows that means of production of our societies have an even more widespread, deep and allegedly unexpected impact on the biology of animals and plants. The microorganism can indeed adapt to resist the selective toxicity of antibiotics. Moreover, bacteria can transfer their genetic code horizontally, by touch, so that we can acquire antibiotic resistance by eating food that functions as a vector, by hosting lice on our heads and many other contacts. Bacteria that are resistant to antibiotics that have been used as growth factors in animal husbandry and to prevent diseases in livestock and aquaculture, spread in natural ecosystems and can be found in wild species. Rivers and estuarine waters are places hosting antibiotic resistance.

Searching on PubMed (the search engine for biomedical literature) titles of articles containing the terms ‘antimicrobial’ and ‘Louisiana’ I retrieved just one twelve-years-old article. No results with terms such as 'Mississippi' or 'New Orleans'. The authors collected and analysed Oysters from both waters of Louisiana Gulf and in restaurants and food retailers in Baton Rouge. In most of the samples gathered, scientists recognised the presence of bacteria (Vibrio parahaemolyticus and Vibrio vulnificus) resistant to specific antimicrobials. Food production is indeed the first factor in terms of the quantity of antibiotics used. This use and related antibiotic resistance impact all the living beings present in a specific area, and can easily travel around the globe through many channels. As Littman & Viens have highlighted, a sustainable future is a future without antibiotics as “there may be no truly sustainable way of using antibiotics in the long-run, as microorganisms have shown to be almost infinitely adaptable since the first introduction of antibiotics” (Littman & Viens 2015). But in the meanwhile, we need to use them and antibiotic resistance is a phenomenon that can be better studied through environmental research, by analysing wild species and emissions nearby livestock, for instance.

The study that I retrieved focuses on Oysters. But what about antibiotic resistance conveyed through food that is consumed by the most?

What about exposures of communities that are living in highly polluted areas?

And what is the additive value on antibiotic resistance for individuals who experience the presence of industrial pollutants and that live in areas where cancer epidemics are registered?

In this respect, there is a strategy to cope with the issue of antibiotic resistance promoted by the Center for Disease Control and Prevention. The document doesn’t mention any action to monitor and regulate the production and usage of antibiotics in livestock. Nevertheless, the CDC wants to scrutinise, through genome sequencing, “Listeria, Salmonella, Campylobacter, and E. coli and uploads sequence data into PulseNet for nationwide monitoring of outbreaks and trends.” Moreover, the document reports that “In Fiscal Year 2019, Louisiana will begin simultaneously monitoring these isolates for resistance genes. When outbreaks are detected, local CDC-supported epidemiologists investigate the cases to stop spread.”

The questions that I would like to ask (to local ppl, activists, researchers, practitioners..) are:

What could be the epidemiologic characteristics (socioeconomic status, gender, residence..) of the populations more vulnerable to antibiotic resistance?

What is the additive role of antibiotic resistance for people living in highly polluted areas?

What is the impact of antibiotic resistance for people and patients living in areas where cancer incidence is high?

And on the long run I am interested in imagining possible strategies to not only living with the problem but also to tackle the problem itself, which means to develop strategies to answer the questions:

Why antibiotic resistance, which is known since a century, it’s a problem on the rise?

What is the role and interest of capitalism, in terms of profit-making of corporations, knowledge production and environmental degradation, in not being able to resolve antibiotic resistance?

What can be strategies of local communities to tackle the problem and to promote environmental justice in terms of alliances with ecologists, doctors, epidemiologists and other activists?

1) DOTs: I chose to look into the TB-control program cited by Paul Farmer and several other global health experts. While this is a minute detail, it seems to be a program which encompasses everything wrong with our current model of biosecurity.

2) Doctors without Borders: Despite reading about this organization multiple times, I've yet to do in-depth research on its goals and capabilities. Recent information seems to indicate DWB (or MSF) struggles to be effective in a long-term way in many of its projects.

3) BSE and food safety: It's been quite a while since mad cow disease has reared its misfolded protein head, but it remains a speck on the public health radar. How agencies balance BSE outbreaks and public opinion can often indicate their level of success, both in terms of job fulfillment and ability to minimize public panic. 

1) NIST: The National Institute of Standards and Technology, a federal agency primarily charged with promoting innovation and industrial competitiveness. In the wake of 9/11, FEMA chose this institution as the leading body in the investigation. This choice seems odd, as NIST is not a regulatory agency; what this agency exactly accomplishes would be interesting to know.

2) ASCE: Prior to reading this article, I had never heard of the ASCE. It serves as a representation of Civil Engineering for American engineers. I'd be intrigued to know their role in worldwide disasters. 

3) War of 1812: Nobody knows what happened during this war; literally the most misunderstood war in American history, yet it serves as a main point of contrast for this article.

It's unclear who, at this time, primarily views and utilizes the information presented here. However, this web platform seems to be one piece of an ongoing project called "Land of Opportunity". This film discusses the ongoing urban issues and developments in America; as we move forward from disasters and begin rebuilding, the question becomes how we want to fortify our cities. The film itself specifically focuses on Hurricane Katrina, while the interactive web platform inclides information about Hurricane Sandy. The film has had several showings, has DVD's for purchase, and a viewing request can also be made.

As mentioned earlier, the bibliography provides several of the authors' own works as references/supporting works for the report. These include reports and specific studies. Additionally, there are several governmental and agency reports, giving credit to this report as an overarching review of the process and not being too narrowly scoped. It should be noted the bibliography also includes several psychological and psychiatric works, detailing nuances of mental illness and their respective prevalence. 

The major actions from the film is the rise of a grassroots organization. The former residents of Camp Lejeune demand answers and action from the Marine Corps. In 2012, the organization saw the successful passing of legislation (called the Janey Ensminger act) authorizing medical care to families and service members who lived at Camp Lejeune from 1957-1987. As mentioned previously, the film highly emphasizes the power of public to have a hand in policy formation if they are willing to put in the time and effort.