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I situate my research at the crossroads of history, philosophy, sociology and anthropology of science. In the past, I have focused on epigenetics, environmental research, empirical bioethics and environmental justice, within and outside the academia, as you can read here, or here. Now I am focusing on antibiotic resistance, and I use it as a lens to interpret the contradictions of the last century derived by industrial production, environmental degradation and biomedical cultures.

What interests me is the (at that time) new epistemic discourse that since the Forties has been produced to explain morphological changes of organisms produce when they experience new environmental conditions or perturbations. Through an important experiment at the base of the so-called concept of genetic assimilation, Conrad H. Waddington showed that a thermic shock can produce changes in wings’ veins of fruit flies, changes that can eventually be inherited across generations, without the environmental trigger that caused them.

This focus on production and (genetic) storage of biological differences elicited by the environment is nowadays coupled with the knowledge produced through microbiome research that explains the phenotypic patterns that recur across generations.

In a thought-provoking twist, with microbiome research, the focus shifts from production and inheritance of biological differences to production and inheritance of biological similarities. Microbiome research shows that some phenotypic patterns are allowed by ecological communities of microorganisms composing all animals. Bacteria allow the development and functioning of our bodies within an epistemic framework that is now key to understand biology. The network of vessels composing mammals’ stomach is formed through cellular differentiation and expression of genes coordinated by bacteria. The same is true for our immune system that is coordinated by gut bacteria. Food, which is an important aspect of our lives also impacts on this microecology and mediates between our biological functions and functioning of means of production whose parts dedicated to food production have immense importance for our biology and our internal and external ecologies. Antibiotic resistance is one of the crossroads where culture, biology, history and the Anthropocene meet. Indeed, Antibiotic resistance shows that means of production of our societies have an even more widespread, deep and allegedly unexpected impact on the biology of animals and plants. The microorganism can indeed adapt to resist the selective toxicity of antibiotics. Moreover, bacteria can transfer their genetic code horizontally, by touch, so that we can acquire antibiotic resistance by eating food that functions as a vector, by hosting lice on our heads and many other contacts. Bacteria that are resistant to antibiotics that have been used as growth factors in animal husbandry and to prevent diseases in livestock and aquaculture, spread in natural ecosystems and can be found in wild species. Rivers and estuarine waters are places hosting antibiotic resistance.

Searching on PubMed (the search engine for biomedical literature) titles of articles containing the terms ‘antimicrobial’ and ‘Louisiana’ I retrieved just one twelve-years-old article. No results with terms such as 'Mississippi' or 'New Orleans'. The authors collected and analysed Oysters from both waters of Louisiana Gulf and in restaurants and food retailers in Baton Rouge. In most of the samples gathered, scientists recognised the presence of bacteria (Vibrio parahaemolyticus and Vibrio vulnificus) resistant to specific antimicrobials. Food production is indeed the first factor in terms of the quantity of antibiotics used. This use and related antibiotic resistance impact all the living beings present in a specific area, and can easily travel around the globe through many channels. As Littman & Viens have highlighted, a sustainable future is a future without antibiotics as “there may be no truly sustainable way of using antibiotics in the long-run, as microorganisms have shown to be almost infinitely adaptable since the first introduction of antibiotics” (Littman & Viens 2015). But in the meanwhile, we need to use them and antibiotic resistance is a phenomenon that can be better studied through environmental research, by analysing wild species and emissions nearby livestock, for instance.

The study that I retrieved focuses on Oysters. But what about antibiotic resistance conveyed through food that is consumed by the most?

What about exposures of communities that are living in highly polluted areas?

And what is the additive value on antibiotic resistance for individuals who experience the presence of industrial pollutants and that live in areas where cancer epidemics are registered?

In this respect, there is a strategy to cope with the issue of antibiotic resistance promoted by the Center for Disease Control and Prevention. The document doesn’t mention any action to monitor and regulate the production and usage of antibiotics in livestock. Nevertheless, the CDC wants to scrutinise, through genome sequencing, “Listeria, Salmonella, Campylobacter, and E. coli and uploads sequence data into PulseNet for nationwide monitoring of outbreaks and trends.” Moreover, the document reports that “In Fiscal Year 2019, Louisiana will begin simultaneously monitoring these isolates for resistance genes. When outbreaks are detected, local CDC-supported epidemiologists investigate the cases to stop spread.”

The questions that I would like to ask (to local ppl, activists, researchers, practitioners..) are:

What could be the epidemiologic characteristics (socioeconomic status, gender, residence..) of the populations more vulnerable to antibiotic resistance?

What is the additive role of antibiotic resistance for people living in highly polluted areas?

What is the impact of antibiotic resistance for people and patients living in areas where cancer incidence is high?

And on the long run I am interested in imagining possible strategies to not only living with the problem but also to tackle the problem itself, which means to develop strategies to answer the questions:

Why antibiotic resistance, which is known since a century, it’s a problem on the rise?

What is the role and interest of capitalism, in terms of profit-making of corporations, knowledge production and environmental degradation, in not being able to resolve antibiotic resistance?

What can be strategies of local communities to tackle the problem and to promote environmental justice in terms of alliances with ecologists, doctors, epidemiologists and other activists?

I'm interested in better understanding the ongoing geological processes that shape St. Louis and the Mississippi Valley region. So far, I've been looking into the history of seismicity in the region, focusing on the fascinating but little known history of the New Madrid earthquakes of 1811 and 1812 -- the most devastating earthquakes to have hit the US east of the Rockies. I've also been exploring how St. Louis and surrounding areas are dealing with the possibility of another earthquake occurring in the future. According to one article I read, one of the biggest uncertainties is what would happen to the heavily engineered Mississippi River in the case of another major tremblor. The shaking could break the levees, flooding wide areas along the river and creating cascading effects. The flow of the river might also reverse completely, as occurred during the New Madrid earthquakes.

On these possibilities and the lack of scientific consensus surrounding intraplate seismicity in this zone, see this article in The Atlantic.

On current efforts to create earthquake hazard maps in St. Louis, see this overview on the US Geological Survey site.

For a deeper dive into the history of the New Madrid earthquakes, see this book by historian of science Conevery Bolton Valencius. 

The main argument is that the cultural translation of a patient’s history is a very complex and difficult process, and can almost eliminate any chance at getting to the root of the patient’s problem.

Fukishima's emergency response, public and corporate messages on Indian Point, Entergy Corporation

"To return to the story: with humanitarians effectively governing in crisis zones, it is not surprising that gender-based violence should become an issue; having been categorised as a human rights violation, one which garnered significant attention, it could not be easily ignored or brushed aside as a ‘private’ matter. Still, approaching gender-based violence as a humanitarian issue required some translation. Humanitarians are primarily concerned with saving lives and relieving suffering; humanitarianism of the sort practised by MSF is most significantly focused on health, and the lives and wellbeing of populations."

"The complications of treating gender-based violence as a humanitarian issue were raised early on by MSF in their work in the Congo Republic. In his essay, Marc Le Pape discusses how, because of rape and violence perpetrated by groups of armed men who set up roadblocks and then proceeded to do as they pleased with those they trapped, humanitarians had to decide whether to accept military escorts on aid convoys to protect against such roadblocks, again with serious political repercussions. Caritas did eventually allow trucks to carry military escorts, yet these escorts in turn invited their friends – armed militiamen – onto the trucks, even as they carried with them the spoils of their plunder"

"Humanitarianism’s mission has expanded so that it now occupies a dominant place in the global political arena – whether humanitarians asked for this or not. But the incorporation of genderbased violence shows humanitarianism at its limit; gender relations and gender-based violence cannot be contained by forms of crisis-driven, moral and medical intervention. In other words, this type of politics based on protecting a universal humanity cannot do all our political work for us; such violence renders visible inequalities that are simply unmanageable and unchangeable by its methods."

The entire study is focused on vulnerable populations – particularly those who due to racial or economic divides, do not have proper access to healthcare, or may be affected by factors such as poor housing and malnutrition.

Emergency response is incrediably relevant to this article. Although a lot of the focus is on humanitarian aid, EMS has these same issues. We have limitations on how much information about a patient we can discuss, although more information is available for statistical use. It is also hard in the short period of time with a patient to fully understand a lot of this information, and we don't go into the field as researchers. Finally, motive is completely unimportant to us most of the time. We see what is wrong and we treat it, we can't worry why the person has a laceration, that is the job of the police, except in the cases of child or elder abuse.

"Through close examination of concrete settings in which biosecurity interventions are being articulated, these chapters show that ways of understanding and intervening in contemporary threats to healt are still in formation: 'biosecurity' does not name stable or cleary define understanding and strategies, but rather a number of overlapping and rapidly changing problem areas."

"After considerable delay, we have recently seen the implementation of large-scale responses to these new infectious desiease threats that bring together governmental, multilater, and philanthropic organizations."

"...newly perceived threats to health... have placed greater pressure on public health departments and national security officials to develop an approach to disease events not easily managed thorugh the traditional paradigm of public health."

Scott Gabriel Knowles is the head of the Department of History at the University of Drexel College of Arts and Sciences. His work focuses on risk and disaster, with particular interest in modern cities, technology and public policy. He is a research fellow at the Disaster Research Center at the University of Delaware, and has been a member of the Fukishima Forum collaborative research community since its inception in 2011. His work on public policy in relation to disaster-preparedness is focused on his home city of Philidelphia, and has written extensively on how to better prepare the city and preserve its legacy.

Mission statement "The Center for Prisoner Health and Human Rights seeks to improve the health and human rights of criminal justice populations through education, research, and advocacy."

The Center for Prisoner Health and Human Rights wants to use research on at-risk populations, such as those in prisons, and develope strategies into sustainable laws. Because this vision spans both the healthcare and policy for prisoners the program hopes to be able to attain this goal more effectively than if it were not interdisciplinary. A large part of their platform is advocacy. They wish to inform policy makers, healthcare professionals and indsutry, and the public about prisoners' lives and needs.