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"Antibiotic Resistance in Louisiana"

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I situate my research at the crossroads of history, philosophy, sociology and anthropology of science. In the past, I have focused on epigenetics, environmental research, empirical bioethics and environmental justice, within and outside the academia, as you can read here, or here. Now I am focusing on antibiotic resistance, and I use it as a lens to interpret the contradictions of the last century derived by industrial production, environmental degradation and biomedical cultures.

What interests me is the (at that time) new epistemic discourse that since the Forties has been produced to explain morphological changes of organisms produce when they experience new environmental conditions or perturbations. Through an important experiment at the base of the so-called concept of genetic assimilation, Conrad H. Waddington showed that a thermic shock can produce changes in wings’ veins of fruit flies, changes that can eventually be inherited across generations, without the environmental trigger that caused them.

This focus on production and (genetic) storage of biological differences elicited by the environment is nowadays coupled with the knowledge produced through microbiome research that explains the phenotypic patterns that recur across generations.

In a thought-provoking twist, with microbiome research, the focus shifts from production and inheritance of biological differences to production and inheritance of biological similarities. Microbiome research shows that some phenotypic patterns are allowed by ecological communities of microorganisms composing all animals. Bacteria allow the development and functioning of our bodies within an epistemic framework that is now key to understand biology. The network of vessels composing mammals’ stomach is formed through cellular differentiation and expression of genes coordinated by bacteria. The same is true for our immune system that is coordinated by gut bacteria. Food, which is an important aspect of our lives also impacts on this microecology and mediates between our biological functions and functioning of means of production whose parts dedicated to food production have immense importance for our biology and our internal and external ecologies. Antibiotic resistance is one of the crossroads where culture, biology, history and the Anthropocene meet. Indeed, Antibiotic resistance shows that means of production of our societies have an even more widespread, deep and allegedly unexpected impact on the biology of animals and plants. The microorganism can indeed adapt to resist the selective toxicity of antibiotics. Moreover, bacteria can transfer their genetic code horizontally, by touch, so that we can acquire antibiotic resistance by eating food that functions as a vector, by hosting lice on our heads and many other contacts. Bacteria that are resistant to antibiotics that have been used as growth factors in animal husbandry and to prevent diseases in livestock and aquaculture, spread in natural ecosystems and can be found in wild species. Rivers and estuarine waters are places hosting antibiotic resistance.

Searching on PubMed (the search engine for biomedical literature) titles of articles containing the terms ‘antimicrobial’ and ‘Louisiana’ I retrieved just one twelve-years-old article. No results with terms such as 'Mississippi' or 'New Orleans'. The authors collected and analysed Oysters from both waters of Louisiana Gulf and in restaurants and food retailers in Baton Rouge. In most of the samples gathered, scientists recognised the presence of bacteria (Vibrio parahaemolyticus and Vibrio vulnificus) resistant to specific antimicrobials. Food production is indeed the first factor in terms of the quantity of antibiotics used. This use and related antibiotic resistance impact all the living beings present in a specific area, and can easily travel around the globe through many channels. As Littman & Viens have highlighted, a sustainable future is a future without antibiotics as “there may be no truly sustainable way of using antibiotics in the long-run, as microorganisms have shown to be almost infinitely adaptable since the first introduction of antibiotics” (Littman & Viens 2015). But in the meanwhile, we need to use them and antibiotic resistance is a phenomenon that can be better studied through environmental research, by analysing wild species and emissions nearby livestock, for instance.

The study that I retrieved focuses on Oysters. But what about antibiotic resistance conveyed through food that is consumed by the most?

What about exposures of communities that are living in highly polluted areas?

And what is the additive value on antibiotic resistance for individuals who experience the presence of industrial pollutants and that live in areas where cancer epidemics are registered?

In this respect, there is a strategy to cope with the issue of antibiotic resistance promoted by the Center for Disease Control and Prevention. The document doesn’t mention any action to monitor and regulate the production and usage of antibiotics in livestock. Nevertheless, the CDC wants to scrutinise, through genome sequencing, “Listeria, Salmonella, Campylobacter, and E. coli and uploads sequence data into PulseNet for nationwide monitoring of outbreaks and trends.” Moreover, the document reports that “In Fiscal Year 2019, Louisiana will begin simultaneously monitoring these isolates for resistance genes. When outbreaks are detected, local CDC-supported epidemiologists investigate the cases to stop spread.”

The questions that I would like to ask (to local ppl, activists, researchers, practitioners..) are:

What could be the epidemiologic characteristics (socioeconomic status, gender, residence..) of the populations more vulnerable to antibiotic resistance?

What is the additive role of antibiotic resistance for people living in highly polluted areas?

What is the impact of antibiotic resistance for people and patients living in areas where cancer incidence is high?

 

And on the long run I am interested in imagining possible strategies to not only living with the problem but also to tackle the problem itself, which means to develop strategies to answer the questions:

Why antibiotic resistance, which is known since a century, it’s a problem on the rise?

What is the role and interest of capitalism, in terms of profit-making of corporations, knowledge production and environmental degradation, in not being able to resolve antibiotic resistance?

What can be strategies of local communities to tackle the problem and to promote environmental justice in terms of alliances with ecologists, doctors, epidemiologists and other activists?

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They also have a fantastic list of these on their website:

Alliance for Global Justice is an organization that seeks to achieve social change and economic justice by helping to build a stronger more unified grassroots movement.

Arts and Democracy builds the momentum of a growing movement that links arts and culture, participatory democracy, and social justice.

Cowbird is a community of storytellers and the beautiful platform that we partnered with to collect and display stories in our first year.

Coney Island Generational Gap is a youth group in Coney Island that organizes work programs, arts opportunities and media courses for more than one hundred youth in the neighborhood.

El Centro is a storefront immigrant day worker center in Port Richmond, Staten Island.

Housing is a Human Right is a creative storytelling project that aims to help connect diverse communities around housing, land, and the dignity of a place to call home.

Interoccupy.Net fosters communication across the Occupy movement.

Land of Opportunity is an ongoing trans-media documentary that captures the struggle to rebuild New Orleans, one of America’s most beloved and emblematic cities. We partnered with Land of Opportunity on Katrina/Sandy.

New York Public Library has been an essential provider of free books, information, ideas, and education for all New Yorkers for more than 100 years.

New York Writers Coalition provides free creative writing workshops throughout New York City for people from groups that have been historically deprived of voice in our society.

Occupy Sandy is a mutual aid network responding to the ongoing crisis in the wake of Hurricane Sandy.

Parsons: New School for Design has been a pioneer in art and design higher education since its founding in 1896.

Project Hope offered free and confidential supportive counseling and public education services to Hurricane Sandy disaster survivors in New York City and Nassau, Suffolk, Rockland, and Westchester Counties in the immediate aftermath of the storm.

Research Action Design (RAD) uses community-led research, transformative media organizing, technology development, and collaborative design to build the power of grassroots social movements.

The Beacon School is a public magnet high school on the Upper West Side that offers an inquiry-based college preparatory program with technology and arts infused throughout the curriculum.

The Hudson School is a private school in Hoboken, New Jersey, that provides intellectually inquisitive students in grades 5-12 with a rigorous and relevant college-preparatory education.

The MIT Center for Civic Media works hand in hand with diverse communities to collaboratively create, design, deploy, and assess civic media tools and practices–including the text and phone technology that Sandy Storyline uses.

YANA (You Are Never Alone) is a worker training center and hurricane relief hub in Rockaway Park.

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"At this point, the burden of mental disorders after disasters has been well documented, and interest in the course of trajectory of psychological symptoms following disasters is growing."

"Persons who live in a community where a disaster hsa occured may differ in their degree of exposure in the event. They may be affected directly, being present at the disaster site, or indirectly, having loved ones present at the disaster site or seeing images of the disaster in the media."

"Ongoing stressors such as job loss, property damage, marital stress, physical health conditions related to the disaster, and displacement are often experienced by those affected by the disaster... Low levels of and reductions in social support are also associated iwth post-disaster psychological symptoms."

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Professor Adriana Petryna teaches Anthropology at UPenn. She focuses on science and technology, globalization and health, and medical anthropology. Her focuses are intertwined with DSTS Network at times, studying incidents of interest such as this article on Chernobyl, and at other times focuses on systemic health issues in socities. 

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Byron J. Good, the author of this book is currently a professor of Medical Anthropology at Harvard, with his research focusing on mental health services development in Asian societies, particularly in Indonesia. He has done collaborative work with the International Organization for Migration on developing mental health services in post-tsunami and post-conflict Aceh, Indonesia. More broadly, he works on the theorization of subjectivity in contemporary societies.

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Entergy Corporation - Owner of Indian Point Plant, Disaster Accountability Project - Nonprofit disaster response 'auditing' organization, Nuclear Regulatory Commission, Steven Peterson - Director of Emergency Management, Ulster County, NY, Dana Smith - Dutchess County comissioner of emergency response