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I'm interested in better understanding the ongoing geological processes that shape St. Louis and the Mississippi Valley region. So far, I've been looking into the history of seismicity in the region, focusing on the fascinating but little known history of the New Madrid earthquakes of 1811 and 1812 -- the most devastating earthquakes to have hit the US east of the Rockies. I've also been exploring how St. Louis and surrounding areas are dealing with the possibility of another earthquake occurring in the future. According to one article I read, one of the biggest uncertainties is what would happen to the heavily engineered Mississippi River in the case of another major tremblor. The shaking could break the levees, flooding wide areas along the river and creating cascading effects. The flow of the river might also reverse completely, as occurred during the New Madrid earthquakes.

On these possibilities and the lack of scientific consensus surrounding intraplate seismicity in this zone, see this article in The Atlantic.

On current efforts to create earthquake hazard maps in St. Louis, see this overview on the US Geological Survey site.

For a deeper dive into the history of the New Madrid earthquakes, see this book by historian of science Conevery Bolton Valencius. 

1)            In domains of biosecurity: bio-terrorism (smallpox, anthrax, etc.), emerging infectious diseases (AIDS, tuberculosis [TB], malaria, etc.), life science (intention production of various deadly organisms for research or otherwise), and food safety (animal borne pathogens and diseases like mad cow, E. coli, etc.)

2)            Global health and emergency response: The DOTS (Directly-Observed Treatment, Short-Course) program failed in several areas to be a service-ready anywhere in the globe for drug resistant TB in places like Georgia. The strict regulations in treatment did not account for the variance in doctor training and practices in this area of the world. Its rigidness led to the breakdown of the protocol adherence.

3)            Health security and modernization risks: As the world modernizes, we generate new risks that need to be addressed. For example, in the 20th century, the technological and system advancements in agriculture and food processing have aided in consistent and increased food supply, but also introduced new problems such as sanitation practices and diseases that led to the creation of the Food and Drug Administration and the expansion of the Department of Agriculture.