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"Antibiotic Resistance in Louisiana"

fdabramo

I situate my research at the crossroads of history, philosophy, sociology and anthropology of science. In the past, I have focused on epigenetics, environmental research, empirical bioethics and environmental justice, within and outside the academia, as you can read here, or here. Now I am focusing on antibiotic resistance, and I use it as a lens to interpret the contradictions of the last century derived by industrial production, environmental degradation and biomedical cultures.

What interests me is the (at that time) new epistemic discourse that since the Forties has been produced to explain morphological changes of organisms produce when they experience new environmental conditions or perturbations. Through an important experiment at the base of the so-called concept of genetic assimilation, Conrad H. Waddington showed that a thermic shock can produce changes in wings’ veins of fruit flies, changes that can eventually be inherited across generations, without the environmental trigger that caused them.

This focus on production and (genetic) storage of biological differences elicited by the environment is nowadays coupled with the knowledge produced through microbiome research that explains the phenotypic patterns that recur across generations.

In a thought-provoking twist, with microbiome research, the focus shifts from production and inheritance of biological differences to production and inheritance of biological similarities. Microbiome research shows that some phenotypic patterns are allowed by ecological communities of microorganisms composing all animals. Bacteria allow the development and functioning of our bodies within an epistemic framework that is now key to understand biology. The network of vessels composing mammals’ stomach is formed through cellular differentiation and expression of genes coordinated by bacteria. The same is true for our immune system that is coordinated by gut bacteria. Food, which is an important aspect of our lives also impacts on this microecology and mediates between our biological functions and functioning of means of production whose parts dedicated to food production have immense importance for our biology and our internal and external ecologies. Antibiotic resistance is one of the crossroads where culture, biology, history and the Anthropocene meet. Indeed, Antibiotic resistance shows that means of production of our societies have an even more widespread, deep and allegedly unexpected impact on the biology of animals and plants. The microorganism can indeed adapt to resist the selective toxicity of antibiotics. Moreover, bacteria can transfer their genetic code horizontally, by touch, so that we can acquire antibiotic resistance by eating food that functions as a vector, by hosting lice on our heads and many other contacts. Bacteria that are resistant to antibiotics that have been used as growth factors in animal husbandry and to prevent diseases in livestock and aquaculture, spread in natural ecosystems and can be found in wild species. Rivers and estuarine waters are places hosting antibiotic resistance.

Searching on PubMed (the search engine for biomedical literature) titles of articles containing the terms ‘antimicrobial’ and ‘Louisiana’ I retrieved just one twelve-years-old article. No results with terms such as 'Mississippi' or 'New Orleans'. The authors collected and analysed Oysters from both waters of Louisiana Gulf and in restaurants and food retailers in Baton Rouge. In most of the samples gathered, scientists recognised the presence of bacteria (Vibrio parahaemolyticus and Vibrio vulnificus) resistant to specific antimicrobials. Food production is indeed the first factor in terms of the quantity of antibiotics used. This use and related antibiotic resistance impact all the living beings present in a specific area, and can easily travel around the globe through many channels. As Littman & Viens have highlighted, a sustainable future is a future without antibiotics as “there may be no truly sustainable way of using antibiotics in the long-run, as microorganisms have shown to be almost infinitely adaptable since the first introduction of antibiotics” (Littman & Viens 2015). But in the meanwhile, we need to use them and antibiotic resistance is a phenomenon that can be better studied through environmental research, by analysing wild species and emissions nearby livestock, for instance.

The study that I retrieved focuses on Oysters. But what about antibiotic resistance conveyed through food that is consumed by the most?

What about exposures of communities that are living in highly polluted areas?

And what is the additive value on antibiotic resistance for individuals who experience the presence of industrial pollutants and that live in areas where cancer epidemics are registered?

In this respect, there is a strategy to cope with the issue of antibiotic resistance promoted by the Center for Disease Control and Prevention. The document doesn’t mention any action to monitor and regulate the production and usage of antibiotics in livestock. Nevertheless, the CDC wants to scrutinise, through genome sequencing, “Listeria, Salmonella, Campylobacter, and E. coli and uploads sequence data into PulseNet for nationwide monitoring of outbreaks and trends.” Moreover, the document reports that “In Fiscal Year 2019, Louisiana will begin simultaneously monitoring these isolates for resistance genes. When outbreaks are detected, local CDC-supported epidemiologists investigate the cases to stop spread.”

The questions that I would like to ask (to local ppl, activists, researchers, practitioners..) are:

What could be the epidemiologic characteristics (socioeconomic status, gender, residence..) of the populations more vulnerable to antibiotic resistance?

What is the additive role of antibiotic resistance for people living in highly polluted areas?

What is the impact of antibiotic resistance for people and patients living in areas where cancer incidence is high?

 

And on the long run I am interested in imagining possible strategies to not only living with the problem but also to tackle the problem itself, which means to develop strategies to answer the questions:

Why antibiotic resistance, which is known since a century, it’s a problem on the rise?

What is the role and interest of capitalism, in terms of profit-making of corporations, knowledge production and environmental degradation, in not being able to resolve antibiotic resistance?

What can be strategies of local communities to tackle the problem and to promote environmental justice in terms of alliances with ecologists, doctors, epidemiologists and other activists?

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Sara_Nesheiwat
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A recent article was published about the technologies that the American Red Cross relies on and offers. Red Cross offers a free mobile app that provides lifesaving information on anyones phone who wants and needs it. Many volunteers utilize this information to be able to respond on scene when necessary. Their national shelter system and home fire geographic information system also helps them map out the best escape routes and prevention methods utilizing technology as well as providing them with fast response alarm times. The American Red Cross also depends on other organizations as well as technologies to help transport people, volunteers, medicine, etc to areas in need. They also depend on other organizations for response orders and collaboration of technologies, resource, hospitals and knowledge. 

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Sara_Nesheiwat

This policy was received in good light by the public for the most part. Patients were only to benefit from this, especially those who lacked insurance. Even those with insurance didn't have to waste time proving it any longer, they were treated and stabilized and insurance issues and payment were brought up later. Any ethically sound doctors, such as the ones working in hospitals that were already implementing the actions set forth by EMTALA (before it was law) had no issues with EMTALA. No doctor should have any issues with it due to their duty to act as well as ethical and moral standards they should be holding themselves up to, written in their oath they took to become doctor. The only people that would stand to receive this act negatively would be the doctors who were actively turning away patients in need, who are clearly morally compromised. Yet, media, patients, a majority of doctors and staff found and received this act positively or with little reservation.

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Sara_Nesheiwat

The topic of biosecurity comes up a lot in this article. The prevalence of this threat is greatly discussed as well as the importance of preparedness. Global health and emergency response efforts are also greatly discussed. Citing emerging diseases as one of the major threats to global security. Public threat response is an aspect that is also widely discussed in this paper as well. Adaptations and improvements in responses are necessary due to new science and technologies that have and are developing. Overall, biosecurity needs to be addressed and threat response improved. 

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Sara_Nesheiwat

Through the use of surveying, this study identified that there are in fact inequalities in people's understanding of proper responses to pandemic influenza outbreaks. This study helped identify these vulnerable groups, and that social media and forms of mass media are the main ways to reach these groups. To address this vulnerable population, the public needs an increased accessibility to information, overall increasing the public's level of knowledge about the pandemic.

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Sara_Nesheiwat

The references show that there was an intense amount of research done by the author. There were a lot of new articles and some studies on disasters in the bibliography. The articles also date back to the times of the actual events, showing an extensive about of work and research on the author's part.

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Sara_Nesheiwat

"This delegitimization was not limited to France. When humanitarian reason was introduced into French law in order to protect sick immigrants against the risk of deportation, it was optimistically thought that, under pressure from nongovernmental organizations..the provision would be extended throughout the Union."

"The logic of state sovereignty in the control of immigration clearly prevailed over the universality of the principle of the right to life."

"Should we accept 'getting our hands dirty' by agreeing to work with the immigrants' service of the prefect's office on the difficult issue of deportations?"

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Sara_Nesheiwat

The program ideology and purpose is based off preparing students for career paths in "(a) communities that are affected by and vulnerable to disaster destruction and disruption; (b) organizations that focus on all phases of disaster management (preparedness, response, recovery, and risk reduction); and, (c) leadership in organizations and communities that require leadership that promotes resilience."

Students can earn a DRLS Master of Science in 2 years (or a 1 year accelerated) and is made up of 36 credits . Courses required to be taken are centered around leaderhsip analytics and environmental hazards. Students are trained and educated under the 5 core competencies or pillars- Human and social factors, Economics of disaster, Environmental and Infrastructure, disaster operations, measurement and evaluation. The goal is to produce competent practitioners in disaster relief, create partnerships within the academic community and provide leadership, research and evaluation abilities in their students. 

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Sara_Nesheiwat

This policy was an expansion of the Social Security Act and other federal social welfare programs that date back to 1950. This policy was created to clear up confusions and set down parameters for how mental health should be addressed under this Act and to define what constitutes an IMD under this policy.

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Sara_Nesheiwat

The argument of this paper is supported through the field research of the author and the findings based off that, as well as testimony and interviews from those effected by the disaster. The author also discusses Chernobyl in depth in terms of pre and post disaster, as well as its history and how there was a change in the area after the disaster. There are also statistical analyses and data provided and a detailed assessment of the internal mechanisms of the government and social aspects of the topic.